Registration Dossier

Administrative data

Key value for chemical safety assessment

Toxic effect type:
dose-dependent

Effects on fertility

Description of key information

No developmental effects at maternally toxic doses (rat, rabbit and noeffects of fertility (rat)) were observed.

Effect on fertility: via oral route
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
NOAEL
100 mg/kg bw/day
Study duration:
chronic
Species:
rat
Effect on fertility: via inhalation route
Endpoint conclusion:
no study available
Effect on fertility: via dermal route
Endpoint conclusion:
no study available
Additional information

No developmental effects at maternally toxic doses (rat, rabbit and noeffects of fertility (rat)) were observed.

Effects on developmental toxicity

Description of key information

No developmental effects at maternally toxic doses (rat, rabbit and noeffects of fertility (rat)) were observed.

Effect on developmental toxicity: via oral route
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
NOAEL
100 mg/kg bw/day
Study duration:
chronic
Species:
rabbit
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via dermal route
Endpoint conclusion:
no study available
Additional information

No developmental effects at maternally toxic doses (rat, rabbit and noeffects of fertility (rat)) were observed.

Justification for classification or non-classification