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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

The lethal concentration (LC50) value of 5-nitro-o-anisidine in fish (Pimephales promelas) in a 96 h study on mortality effect was estimated to be     207.4058mg/L. But the BCF value of 5-nitro-o-anisidine reported was not >= 500 as well as the substance was found to be rapidly degradable.Thus considering only the value from CLP Criteria for aquatic classification of the substance , it is concluded that 5-nitro-o-anisidine could not exhibit short term toxicity to fish (Pimephales promelas) 

Key value for chemical safety assessment

LC50 for freshwater fish:
207.406 mg/L

Additional information

The lethal concentration (LC50) value of 5-nitro-o-anisidine in fish (Pimephales promelas) in a 96 h study on mortality effect was estimated to be 207.4058mg/L. The supporting studies also predicted an LC50 value above 207.4 mg/L.

The various weight of evidence studies can be summarised as follows :

Sr. No

Endpoint Name

Value

 Unit  Species  Basis of effect
 1  LC50  207.4058  mg/L  Pimephales promelas  mortality
 2  EC50  139.0646  mg/L  Lepomis macrochirus  mortality
 3  LC50  119.1158  mg/L  Oncorhynchus mykiss  mortality

 

But the BCF value of 5-nitro-o-anisidine reported was not >= 500 as well as the substance was found to be rapidly degradable.Thus considering only the value from CLP Criteria for aquatic classification of the substance , it is concluded that 5-nitro-o-anisidine could not exhibit short term toxicity to fish (Pimephales promelas)