Registration Dossier
Registration Dossier
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EC number: 700-897-5 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
The Key study was performed on an analog substance according to Magnusson-Kligman Maximization Assay,
Induction phase
The assays are run by applying a minimally irritating dose of the test compound (5% propylene glycol and freund's adjuvant) the to the shaved flanks of Dunkin-Hartley guinea pigs for approximately 3 weeks.
Challenge phase
About 1x week after the last application, the undiluted chemical or 50% in petrolatum is re-applied to the animals.
Scoring of erythema and edema (24 and 48 hours) is accomplished by adding up all the animals that responded in a group of ten and expressing it as a percentage (incidence) and determined the intensity of teach response on a scale of 0-4.
Result
Scores of zero in all test animals were obtained at all time points examined. The test material does not appear to be a sensitizer in the guinea pig.
Migrated from Short description of key information:
The Key study was performed on an analog substance according to Magnusson-Kligman Maximization Assay. Scores of zero in all test animals were obtained at all time points examined. The test material does not appear to be a sensitizer in the guinea pig.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
In accordance with EU CLP Regulation (EC) No. 1272/2008, classification of this substance is not required for skin sensitisation.
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