Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP-study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
1.45
Temp.:
25 °C
pH:
7.2
Remarks on result:
other: The reference Pow-values in the OECD guideline 117 presumably refer to 25 °C. Even though the column temperature was 40 °C, this temperature has no influence on the result. Therefore the determined Pow-value of the TS also refers to 25 °C.

Applicant's summary and conclusion

Conclusions:
The partition coefficient of the test item is determined to be log Pow = 1.45.