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EC number: 819-558-9 | CAS number: 2020359-04-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 1-(9,9-dibutyl-9H-fluoren-2-yl)-2-methyl-2-(morpholin-4-yl)propan-1-one
- EC Number:
- 819-558-9
- Cas Number:
- 2020359-04-8
- Molecular formula:
- C29H39NO2
- IUPAC Name:
- 1-(9,9-dibutyl-9H-fluoren-2-yl)-2-methyl-2-(morpholin-4-yl)propan-1-one
- Test material form:
- solid: particulate/powder
- Details on test material:
- a off-white powdery solid, without irritating odor
Constituent 1
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- In the Daphnia sp. breeding room of Centralbio Co., Ltd.
Study design
- Test type:
- static
- Water media type:
- not specified
- Limit test:
- yes
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 20 ± 1°C
- pH:
- 6.00 ~ 9.00.
- Dissolved oxygen:
- not less than 3 mg/L
- Nominal and measured concentrations:
- 1.0, 10.0 and 100.0 mg/L
- Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate (K2Cr2O7).
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 0.006 mg/L
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 0.006 mg/L
- Details on results:
- During the exposure period, the percent immobilisation in the control group was less than 10 %. No abnormal signs or behaviors such as discoloration and trapping of Daphnia magna at the surface of water were evident in the control group. In addition, the dissolved oxygen concentrations in the control group and treatment group were 3 mg/L or more at the end of exposure. Therefore, the results were considered to be acceptable.
Based on the range finding test, limit test was performed in control, and 100.00 mg/L. As a result of the limit test, The geometric mean measured concentration of the test substance at the 100.00 mg/L was 0.00611 mg/L during test period.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- During an exposure period, there was not immobilisation and death at limit test. Therefore EC50 was reported >0.00611 mg/L and NOEC was reported ≥0.00611 mg/L. All results of test were determined based on geometric mean measured concentration.
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