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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
A GLP-compliant short-term fish test on embryo and sac-fry stages was conducted according to OECD 212 with Gobiocypris rarus under semi-static conditions as part of a new chemical substance notification in China. This test is considered as chronic test since it measures the sensitive early life stages from the newly fertilised egg to the end of the sac-fry stage.
Based on nominal concentrations, the 8d-LC10 was 15.4 mg/L, the LC50 was 42.5 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 15.4 mg/L
Additional information
A GLP-compliant short-term fish test on embryo and sac-fry stages was conducted according to OECD 212 with Gobiocypris rarus under semi-static conditions as part of a new chemical substance notification in China. Based on the results of the acute fish test, five treatment groups and a control group were included in the definitive test. The nominal concentrations for the treatment groups were 6.25, 12.5, 25, 50 and 100 mg/L. All treatment groups and blank control group had three replicates each containing 10 embryos and the test duration was 8 days. Since precipitates were formed in the test water, a 24h semi-static test was performed to maintain the concentration of the test substance as much as possible. The hatching success of fertilised eggs and the overal survival of fish larvae in the blank control was 100% and the dissolved oxygen concentration was greater than 70.1% throughout the test. Under the test conditions, based on the nominal concentrations, the 10%, 20% and 50% lethal concentration at the end of the test (LC10, LC20 and LC50) was 15.4, 21.9 and 42.5 mg/L, respectively.
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