Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 614-947-8 | CAS number: 693217-63-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 18 February - 13 April 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP/guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- other: EPA-821-R-02-013
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- Soybean oil, reaction products with ethaneperoxoic acid
- Cas Number:
- 693217-63-9
- Molecular formula:
- C59 H106 O11
- IUPAC Name:
- Soybean oil, reaction products with ethaneperoxoic acid
- Test material form:
- liquid: viscous
- Details on test material:
- Agrol Polyol (CAS# 693217-63-9)
Constituent 1
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
Not applicable.
Sampling and analysis
- Analytical monitoring:
- not specified
- Details on sampling:
- Methanol was used as a vehicle to extract the water soluble portions of the Agrol@ Polyol product. The amount of methanol used was limited to the 100-mg/L outlined in OECD Guidelines. The test material was stirred and then allowed to equilibrate for one hour before the supernatant was used. A concurrent methanol blank was conducted to verify that this solvent did not inhibit growth.
Test solutions
- Vehicle:
- yes
- Details on test solutions:
- Methanol was used as a vehicle to extract the water soluble portions of the Agrol@ Polyol product. The amount of methanol used was limited to the 100-mg/L outlined in OECD Guidelines. A concurrent methanol blank was conducted to verify that this solvent did not inhibit growth.
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- The test organism used in this study was the unicellular coccoid green alga, Selenastrum capricornutum. The original culture was obtained from Aquatic Biosystems, Fort Collins, Co. which in tum was obtained from the University of Texas Culture Collection, Austin, TX (UTEX Number 1648). The culture designation for this report is 10013.SLN. S capricornutum was cultured according to the EPA Short-Term Methods for Estimating the Chronic Toxicity of Effluents and Receiving Water to Freshwater Organisms.
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- No data
- Test temperature:
- During these tests, in all test vessels the temperature remained within the limits established in the Quality Manual. Range was 25.0 - 25.6C.
- pH:
- the pH range was normal. There was a noted increase in pH during the study. Increasing pH in this type of bioassay is normal as the log phase growth of algae occurs. The rate of increase is greatest toward the end of the 96-hour period. Increases of more than I pH unit toward the end of the 96-hour period are normal. Control pH ranged from 6.4 (initial) to 8.7 (after 96 hrs). Initial pH for all test groups of Agrol were within 6.4-6.5. After 96 hrs pH for all test groups of Agrol were within 7.5 - 8.8
- Dissolved oxygen:
- No data.
- Salinity:
- No data.
- Nominal and measured concentrations:
- 0, 0 (methanol control), 6.25, 12, 25, 50 and 100 mg/L extractable fraction of Agrol.
- Details on test conditions:
- Lighting was accomplished with cool-white fluorescent lamps and was measured at between 360 and 440-footcandles. The photoperiod was 24-hours light.
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 12.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- cell number
- Duration:
- 96 h
- Dose descriptor:
- other: IC25
- Effect conc.:
- 60.4 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- cell number
- Duration:
- 96 h
- Dose descriptor:
- IC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- cell number
- Details on results:
- See Table 1.
- Results with reference substance (positive control):
- No data.
- Reported statistics and error estimates:
- 1C25 = 60.357 +/- 5.319 (CI = 42.124-74489)
IC50 = >100
Any other information on results incl. tables
Table 1 96 hour Chronic with S. capricornutum
Test Concentration | Cells/mL (x 106) |
Lab Control, 0 | 1.15 |
Methanol Control, 0 | 1.17 |
6.25 mg/L | 1.20 |
12.5 mg/L | 1.28 |
25 mg/L | 1.07 |
50 mg/L | 0.97 |
100 mg/L | 0.71 |
NOEC | 12.5 mg/L |
IC25 | 60.4 mg/L |
IC50 | >100 mg/L |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The NOEC was 12.5 mg/L and the IC25 and IC50 were 60.4 and >100 mg/L, respectively.
- Executive summary:
A 96 -hour Algal growth inhibition study was conducted with S. capricornutum. The NOEC was 12.5 mg/L and the IC25and IC50were 60.4 and >100 mg/L, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.