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EC number: 607-854-9 | CAS number: 2605-78-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- February 09th, 2005 - July 26th, 2005
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- - Analytical purity: Not available
- Purity test date: Not available
- Lot/batch No.: 75412
- Expiration date of the lot/batch: Not available
- Appearance: Not reported
- Storage: Not reported - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- Secondary sewage effluent was collected from Runcorn East Sewage Works (3rd June 2005). After collection, the inoculum was coarse filtered and allowed to settle for one hour before the supernatant liquid was decanted off for use as the test inoculum.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 5 mg/L
- Based on:
- test mat.
- Initial conc.:
- 6.5 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Nutrient enriched freshwater
- Test temperature: 17.5-18.5°C
- pH adjusted: No
- Continuous darkness: Yes
TEST SYSTEM
- Culturing apparatus: Completely filled, sealed glass BOD bottles of nominal 272 ml volume
- Number of culture flasks/concentration: 2 bottles per sampling day for the test material and the reference material vessels, 3 bottles per sampling day for the control (blank) vessels
- Test performed in closed vessels due to significant volatility of test substance: No
- Test performed in open system: No (closed bottle method)
SAMPLING
- Sampling frequency: Dissolved oxygen measured on sample days 0, 3, 7, 14, 21 and 28
- Sample storage before analysis: Used on day of preparation
CONTROL AND BLANK SYSTEM
- Inoculum blank: Yes (3 bottles per sampling day)
- Abiotic sterile control: No
- Toxicity control: No - Reference substance:
- benzoic acid, sodium salt
- Remarks:
- 2.5mg/l
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 86.8
- Sampling time:
- 7 d
- Remarks on result:
- other: 5.0 mg test material/L
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- > 100
- Sampling time:
- 28 d
- Remarks on result:
- other: 5.0 mg test material/L
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 85.1
- Sampling time:
- 7 d
- Remarks on result:
- other: 6.5 mg test material/L
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- > 100
- Sampling time:
- 28 d
- Remarks on result:
- other: 6.5 mg test material/L
- Results with reference substance:
- A degradation figure of 67.8% after 28 days was obtained for the reference material. This demonstrates that the inoculum was biologically active.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The biodegradation of the test material within 28 days was >100% COD (mean of two replicates) at both 5.0 and 6.5 mg/L, and reached the criteria for ready biodegradability.
- Executive summary:
The aerobic biodegradability of the test material was investigated in a GLP-compliant ready biodegradability study performed in accordance with OECD Guideline No. 301D. The biodegradation of the test material within 28 days was >100% COD (mean of two replicates) at both 5.0 and 6.5 mg/L, and reached the criteria for ready biodegradability.
Reference
Summary of results
% Degradability |
|||||
Material (mgl-1) |
Day 3 |
Day 7 |
Day 14 |
Day 21 |
Day 28 |
Mackam C-8 (5.0) |
4.8 |
86.8 |
92.4 |
90.4 |
>100.0 |
Mackam C-8 (6.5) |
3.1 |
85.1 |
96.4 |
92.2 |
>100.0 |
Sodium benzoate (2.5) |
56.3 |
62.3 |
67.3 |
71.9 |
67.8 |
Description of key information
The aerobic biodegradability of the test material was investigated in a GLP-compliant ready biodegradability study performed in accordance with OECD Guideline No. 301D. The biodegradation of the test material within 28 days was >100% COD (mean of two replicates) at both 5.0 and 6.5 mg/L, and reached the criteria for ready biodegradability.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
The aerobic biodegradability of the test material was investigated in a GLP-compliant ready biodegradability study performed in accordance with standard methods, without deviations. The study is considered as reliable (Klimisch 1) and is selected as a key study for the endpoint.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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