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EC number: 268-859-6 | CAS number: 68152-93-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: simulation testing on ultimate degradation in surface water
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2023
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 309 (Aerobic Mineralisation in Surface Water - Simulation Biodegradation Test)
- Version / remarks:
- April 2004
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Radiolabelling:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- effluent/surface water mixture, untreated
- Details on source and properties of surface water:
- A sample of Calwich Abbey Lake surface water (Staffordshire, UK) will be supplied by Land Research Associates (Lockington Hall, UK). The location, date and time of collection, depth of sampling of the water and appearance of the water will be recorded. The dissolved oxygen content, temperature, pH and conductivity of the water will be recorded at the time of collection. The water will be sieved (0.1 mm) prior to use on this study.
The surface water should be used as quickly as possible (within 1 week of collection). On receipt and until preparation of the test samples, the water will be stored in the dark under aerobic conditions at ca +4 °C. - Parameter followed for biodegradation estimation:
- CO2 evolution
- Reference substance:
- benzoic acid, sodium salt
- Remarks on result:
- not measured/tested
- Remarks:
- The study could not be initiated as radiolabelled test material was found being not adequate. Thus, new radiolabelled test material is currently produced to start the study with this new batch of radiolabelled material, accordingly.
- Transformation products:
- not specified
- Remarks:
- Results are still outstanding
- Conclusions:
- Currently, the study is still ongoing as it could not be concluded prior to the submission deadline (September 20th, 2022) and the exposure phase on this study will begin presumably in 2023, when new radiolabelled material becomes available. Thereafter, the soil biodegradation examinations will start and a draft report is expected by end of October, 2023. Once available, the robust study summary will be updated and a dossier update will be submitted again.
- Endpoint:
- biodegradation in water: simulation testing on ultimate degradation in surface water
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2023
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 309 (Aerobic Mineralisation in Surface Water - Simulation Biodegradation Test)
- Version / remarks:
- April 2004
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Radiolabelling:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- effluent/surface water mixture, untreated
- Details on source and properties of surface water:
- A sample of Calwich Abbey Lake surface water (Staffordshire, UK) will be supplied by Land Research Associates (Lockington Hall, UK). The location, date and time of collection, depth of sampling of the water and appearance of the water will be recorded. The dissolved oxygen content, temperature, pH and conductivity of the water will be recorded at the time of collection. The water will be sieved (0.1 mm) prior to use on this study.
The surface water should be used as quickly as possible (within 1 week of collection). On receipt and until preparation of the test samples, the water will be stored in the dark under aerobic conditions at ca +4 °C. - Parameter followed for biodegradation estimation:
- CO2 evolution
- Reference substance:
- benzoic acid, sodium salt
- Remarks on result:
- not measured/tested
- Remarks:
- The study could not be initiated as radiolabelled test material was found being not adequate. Thus, new radiolabelled test material is currently produced to start the study with this new batch of radiolabelled material, accordingly.
- Transformation products:
- not specified
- Remarks:
- Results are still outstanding
- Conclusions:
- Currently, the study is still ongoing as it could not be concluded prior to the submission deadline (September 20th, 2022) and the exposure phase on this study will begin presumably in 2023, when new radiolabelled material becomes available. Thereafter, the soil biodegradation examinations will start and a draft report is expected by end of October, 2023. Once available, the robust study summary will be updated and a dossier update will be submitted again.
Referenceopen allclose all
Description of key information
To fulfill the testing requirement for ultimate degradation in surface water for the UVCB substance, the two main constituents were selected as surrogates for investigation. Maleated tall-oil fatty acid (CAS 6935-55-3) and maleated rosin (CAS 4559-23-3) were individually synthesized by reacting linoleic acid and rosin, respectively, with 14C-radiolabelled maleic anhydride, where one of the two carbonyl atoms was labelled with 14C. The two radiolabelled model substances were individually investigated in an OECD 309 study protocol.
Unfortunately, the radiolabelled test specimen, when arriving in the test facility, already had degraded significantly and thus, the requirement for >=95% radiolabelling was not fulfilled anymore. Hence, the biodegradation study could not be initiated as planned and radiolabelled material has to be re-synthesized first.
This has lead to significant delays and the two studies are not concluded. Once degradation results and a final report become available, the dossier will be updated.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.