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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 242-604-9 | CAS number: 18824-74-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 48 hours
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- EPA review document covering tetrabromophthalates.
Substance in test was the anhydride, but this hydrolyses rapidly in water to the acid.
This is considered a valid substitute for read-across as the potassium salt will quickly dissociate; when diluted in solution, both the potassium salt and acid will combine with Calcium and Magnesium ions in natural water and form poorly soluble salts.
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unnamed
- Year:
- 1 999
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EPA OPPTS 850.1010 (Aquatic Invertebrate Acute Toxicity Test, Freshwater Daphnids)
- Principles of method if other than guideline:
- Full details of method not preovided in the review, but noted to be in accordance with national guidelines
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Tetrabromophthalic acid
- Cas Number:
- 13810-83-8
- Molecular formula:
- C8H2Br4O4
- IUPAC Name:
- Tetrabromophthalic acid
Constituent 1
- Specific details on test material used for the study:
- Substance in test was an alkyl ester, shown to react in light to quickly hydrolyse in water to the acid. The data relates to the acid form.
Bis(2-ethylhexyl) tetrabromophthalate, EC 247-426-5 hydrolysis shows rapid degradation to tetrabromophthalic acid ( Source: European Chemicals Agency, http://echa.europa.eu/)
This is considered a valid substitute for read-across as the potassium salt will quickly dissociate; when diluted in solution, both the potassium salt and acid will combine with Calcium and Magnesium ions in natural water and form poorly soluble salts.
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- Not specified, but performed within guidline parameters
- Test temperature:
- Not specified, but performed within guidline parameters
- pH:
- Non-adjusted
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC0
- Effect conc.:
- > 5.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- There was no reported effect at limit of solubility
Substance in test was the anhydride, but this hydrolyses rapidly in water to the acid.
This is considered a valid substitute for read-across as the potassium salt will quickly dissociate; when diluted in solution, both the potassium salt and acid will combine with Calcium and Magnesium ions in natural water and form poorly soluble salts.
Applicant's summary and conclusion
- Conclusions:
- Substance in test was the anhydride, but this hydrolyses rapidly in water to the acid.
This is considered a valid substitute for read-across as the potassium salt will quickly dissociate; when diluted in solution, both the potassium salt and acid will combine with Calcium and Magnesium ions in natural water and form poorly soluble salts.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.