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EC number: 221-435-4 | CAS number: 3091-25-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 28th June to 6th August 2002
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Study conducted in compliance with agreed protocols, with minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. This study was in accordance with the OECD principles of Good Laboratory Practice (GLP).
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 003
- Report date:
- 2003
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- yes
- Remarks:
- additional NaNO3 was added to the mineral medium to prevent nitrogen limitation
- Principles of method if other than guideline:
- No information.
- GLP compliance:
- yes
Test material
- Reference substance name:
- Trichlorooctylstannane
- EC Number:
- 221-435-4
- EC Name:
- Trichlorooctylstannane
- Cas Number:
- 3091-25-6
- Molecular formula:
- C8H17Cl3Sn
- IUPAC Name:
- trichlorooctylstannane
- Reference substance name:
- MOTC
- IUPAC Name:
- MOTC
- Details on test material:
- - Name of test material (as cited in study report): trichlorooctylstannane
- Molecular formula (if other than submission substance): C8Hl7Cl3Sn
- Molecular weight (if other than submission substance): 338.3 g/mol
- Physical state: colourless liquid
- Analytical purity: 100%
- ThOD NH3: 1.16 mg O2/mg
- Solubility in water: 0.33 mg/L
- Melting point: <10 degrees C
- Density: 1.41-1.45 g/cm^3 (at 20 ºC)
- Storage temperature range: <-18 ºC
- Protect from light: yes
- ORTEP Lot no.: W 00/78
- Research production number: TF 03443
- Expiry date: 31 July 2004
- TNO test substance number: 2496
- Date of receipt: 31 July 2001
- Quantity: 5 x 100 g
- Supplier: ORTEP Association Stabilizer Task Force
Constituent 1
Constituent 2
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
No information
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- A sample of activated sludge was taken from an oxidation ditch situated in the municipality of Hazerswoude, the Netherlands, on June 26, 2002. The oxidation ditch is used to treat domestic waste water. The activated sludge was transported in a plastic flask and aerated until use. Beofre the start of the test, the dry weight of the sludge was determined to be 4.65 g/L. In order to yield a concentration of solids of approximately 30 mg/L, 1.96 mL sludge was added to 300 mL of mineral medium.
- Duration of test (contact time):
- 39 d
Initial test substance concentration
- Initial conc.:
- 43 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Solubilising agent (type and concentration if used):
- Test temperature: 20.5 ºC
- pH: start of the study: 7.8 - 8.0; end of the study 6.4
- pH adjusted: no
- CEC (meq/100 g): not specified
- Aeration of dilution water: not specified
- Suspended solids concentration: 30 mg/L
- Continuous darkness: yes
- Other: not applicable
TEST SYSTEM
- Culturing apparatus: 500 mL glass flasks
- Number of culture flasks/concentration: 1 flask/concentration
- Method used to create aerobic conditions: not specified
Reference substance
- Reference substance:
- acetic acid, sodium salt
Results and discussion
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0.2
- Sampling time:
- 39 d
- Details on results:
- The BOD values were 0.03, 0.01, 0.00 mg O2/flask after 14, 28, and 39 days of incubation. The corresponding biodegradation percentages were 45, 47 and 49%.
BOD5 / COD results
- Results with reference substance:
- The reference substance was sufficiently degraded within 14 days of incubation (78%). The cumulative oxygen consumption in the toxicity control (sodium acetate and test substance) was 19.5 mg O2/flask after 14 days which was slightly lower than that of the inoculum activity control with sodium acetate only (20.5 mg O2/flask). This indicated that the test substance slighlty inhibited the degradation of sodium acetate at the concentration tested. Based on the combined ThOD of both substances, a biodegradation >25 % was reached, which, according to the guidelines, means that the substance is considerd not toxic to the inoculum.
Any other information on results incl. tables
Table 1: Results of the inoculums activity and toxicity control tests with trichlorooctylstannane: mean values of the cumulative oxygen consumption (mg O2/flask) and biodegradation as percentage of the ThODNH3 (mean values after 14, 28 and 39 days
Time days |
Inoculum blank |
Inoculum activity control1 |
Toxicity control2 |
|||
Without filter mg O2/flask |
With filter mg O2/flask |
mg O2/flask |
Biodegradation ThOD %4 |
mg O2/flask |
Biodegredation ThOD%3 |
|
14 (336 hours) |
4.6 |
3.8 |
20.5 |
78 |
19.5 |
45 |
28 (672 hours) |
6.3 |
5.5 |
22.8 |
82 |
22.1 |
47 |
39 (928 hours) |
6.9 |
6.2 |
23.8 |
84 |
23.3 |
49 |
1 – 100 mg/L sodium acetate
2 – 100 mg/L sodium acetate + 43 mg/L trichlorooctylstannane
3 – Corrected for blank with filter
4 – Corrected for blank without filter
Table 2: Biodegredation of trichlorooctylstannane (43 mg/L) expressed as the BOD (mg O2/mg) and as a percentage of its ThODNH3 (mean values).
Time days |
BOD mg O2/mg |
% Biodegradation ThODNH3 |
14 (336 hours) |
0.03 |
2.5 |
28 (672 hours) |
0.01 |
0.9 |
39 (928 hours) |
0.00 |
0.2 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
- Conclusions:
- The 60 % degradation criterion was not met under the conditions requireed by OECD Guideline 301F, even when the study was extended to 39 days. A maximum degradation of 3.2 % was reached after 18 days of incubation. After 28 days a degradation of 0.9% was noted. Trichlooctylstannane was considered not readily biodegradable.
- Executive summary:
The biodegradation of trichlooctylstannane was determined under "Manometric Respirometry Test" in the OECD Guideline 301F for a period of 39 days at an average temperature of 20.5 ºC. The test method is in agreement with the EU Test Guideline C.4 -D. The test fulfilled the conditions of validity given by the guidelines. The study was also carried out in accordance with the OECD principles of Good Laboratory Practices (GLPs).
A maximum degradation of 3.2 % was reached after 18 days of incubation, and the 60 % degradation criterion was not met under the conditions required by OECD Guideline 301F. After 28 days a degradation of 0.9% was noted. Therefore, trichlooctylstannane was considered not to be readily biodegradable.
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