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Diss Factsheets
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EC number: 214-465-4 | CAS number: 1131-60-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 983
- Report date:
- 1983
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Umweltbundesamt Berlin - Verfahrensvorschlag (F.1.1) "Letale Wirkung beim Zebrabärbling Brachyodanio rerio" (Lethal effects on Brachydanio rerio) (LC0, LC50, LC100, 48-96h)
- Version / remarks:
- 01.06.82
- GLP compliance:
- no
- Remarks:
- Study conducted prior to GLP implementation
Test material
- Reference substance name:
- 4-cyclohexylphenol
- EC Number:
- 214-465-4
- EC Name:
- 4-cyclohexylphenol
- Cas Number:
- 1131-60-8
- Molecular formula:
- C12H16O
- IUPAC Name:
- 4-cyclohexylphenol
Constituent 1
Test solutions
- Vehicle:
- yes
- Remarks:
- prediluted in acetone
- Details on test solutions:
- For the preparation of the stock solution the substance (1g) has been pre-diluted in Acetone (1g) and taken out under stirring with Ultra-Turrax.
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- TEST ORGANISM
- Common name: zebra fish
- Length at study initiation (length definition, mean, range and SD): 30 ± 5 mm
FEEDING DURING TEST
- No feeding during test
Study design
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- 15° dH
- Test temperature:
- 23 ± 2 °C
- pH:
- 7.0 ± 0.2
- Nominal and measured concentrations:
- 1000 mg/L (emuslified)
- Details on test conditions:
- TEST SYSTEM
- Test vessel: Aquarium
- Material, size, headspace, fill volume: fill volume 8.4L, but filled only with 3.5L water
- Aeration: 3 bubbles per second
- No. of organisms per vessel: 10 per 3.5 L
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: reconstituted, demineralised drinking water (by activated carbon & ion exchanger to eliminate Cu)
- Ca/Mg ratio: 4:1
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- 7.5 mg/L
- Conc. based on:
- test mat.
- Duration:
- 96 h
- Dose descriptor:
- LC100
- Effect conc.:
- 8 mg/L
- Conc. based on:
- test mat.
- Details on results:
- LC50 could not be determined due to the steep dose/response curve.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- LC100 (96h) = 8 mg/L
LC0 (96h) = 7.5 mg/L;
LC50 could not be determined due to the steep dose/response curve, but will be ~ 7.7 mg/L. This triggers a classification as Category Chronic 2 as there are no chronic data available and the substance is not readily biodegradable and the logPow > 4.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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