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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
4-acetyl-2-methylbenzoic acid
EC Number:
856-079-4
Cas Number:
55860-35-0
Molecular formula:
C10H10O3
IUPAC Name:
4-acetyl-2-methylbenzoic acid
Test material form:
solid: particulate/powder

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
130.4 °C
Atm. press.:
100.9 kPa
Decomposition:
no
Sublimation:
no

Any other information on results incl. tables

Aliquots of the substance were weighed into aluminium crucibles with manually pierced lids. Four independent determinations of the melting point were done in a differential scanning calorimeter.


Determination 1: 0.0048 g


Determination 2: 0.0050 g


Determination 3: 0.0047 g


Determination 4: 0.0046 g


A Mettler Toledo DSC822 calorimeter with a ThermoHaake Coller EK45/MT was used. The temperatur program was set to heat from 100 to 160 °C at 1 °C/minute. Determinations 1 and 2 were made under nitrogen, determinations 3 and 4 were made under static air atmosphere. The mean melting temperature of the test item was 130.4 °C. A standard deviation of 0.09 °C was calculated from the four replicates. The atmospheric pressure was 100.9 kPa. Essentially identical thermograms were observed in air and nitrogen atmospheres. 

Applicant's summary and conclusion

Conclusions:
The melting temperature of the test substance was determined to be 130.4 °C at a pressure of 100.9 kPa.
Executive summary:

The melting temperature of the test substance was determined under GLP to OECD TG 102, using a differential scanning calorimeter. Aliquots of about 0.005 g of the substance were weighed into aluminium crucibles with manually pierced lids. Four independent determinations of the melting point were done in a differential scanning calorimeter. The temperatur program was set to heat from 100 to 160 °C at 1 °C/minute. Determinations 1 and 2 were made under nitrogen, determinations 3 and 4 were made under static air atmosphere. The mean melting temperature of the test item derived from the thermograms was 130.4 °C. A standard deviation of 0.09 °C was calculated from the four replicates. The atmospheric pressure was 100.9 kPa. Essentially identical thermograms were observed in air and nitrogen atmospheres.