Registration Dossier
Registration Dossier
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EC number: 856-079-4 | CAS number: 55860-35-0
pH
Administrative data
- Endpoint:
- pH
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 122 (Determination of pH, Acidity and Alkalinity)
- Version / remarks:
- 2013
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 4-acetyl-2-methylbenzoic acid
- EC Number:
- 856-079-4
- Cas Number:
- 55860-35-0
- Molecular formula:
- C10H10O3
- IUPAC Name:
- 4-acetyl-2-methylbenzoic acid
- Test material form:
- solid: particulate/powder
Constituent 1
Reagents
- Reagent:
- water
Results and discussion
pH value
- Key result
- pH value:
- 2.85
- Temp.:
- 20 °C
- Concentration:
- 1 vol%
Applicant's summary and conclusion
- Conclusions:
- The pH value of a 1% w/v aqueous dispersion of the substance has been determined to be 2.85 at 20 °C.
- Executive summary:
The pH value of the substance in water was determined under GLP to OECD TG 122. Two independent measurements were performed. An aliquot of test substance (about 1 g) was added to 50 mL of high puritywater. Each sample was then diluted to 100 mL with high purity water before being shaken vigorously for one minute. The high purity water, with a specification of resistance >18.2 MΩ and TOC <5 ppb, was pre-equilibrated to 20 °C before use. Each sample was then transferred to a sample cup, allowed to settle for a period of 1 minute and the pH value then determined. The pH value was recorded from the pH meter, without stirring of the sample, after a period of 1 minute equilibration and a second reading was recorded after a period of 2 minutes equilibration. If the difference between the two readings did not exceed 0.1 pH units, the pH value was considered stable. If a pH drift greater than 0.1 pH units was observed between the two readings, a final pH value reading was taken after 10 minutes equilibration.
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