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Diss Factsheets
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EC number: 410-560-1 | CAS number: 153519-44-9 CGL 400
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Based on the long-term (chronic) toxicity study data, the test substance is very likely not harmful to aquatic invertebrates.
Key value for chemical safety assessment
Additional information
A GLP guideline study according OECD 211 including analytical monitoring has been conducted (BASF SE 2015). Due to the low solubility of the test substance the test solutions were prepared following general guidance provided in OECD 23 in order to achieve a saturated solution (water saturated fraction, WSF) of the test substance. The test solutions were weighed in and prepared separately (differential loading).
After 22 d no significant mortality, reduced reproduction or any other additional significant adverse effects or abnormal behavior were observed in any of the test treatments. Therefore, the LOEC was determined to be > 10 mg/L (loading rate) and the NOEC was determined to be ≥ 10 mg/L (loading rate).
Concerning analytical monitoring, no test substance peaks were measured in any of the control samples over the exposure period. Peaks corresponding to the test substance were measured in many of the samples from the treatments groups, but many others were below the wLOQ. Results were inconsistent and varied widely both within and between treatment groups. There was no pattern of increasing measured concentration corresponding to the loading rate. The measured concentrations do confirm the presence of the test substance in the test vessels, however they are not suitable to derive exposure levels due to the high variability. Since all reasonable efforts were taken to produce saturated solutions of the test substance in test media, following the guidance in OECD 23, the test results should be based on loading rate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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