Registration Dossier
Registration Dossier
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EC number: 454-450-1 | CAS number: 429659-01-8 BIBR 1048 MANAMIDE
Adsorption / desorption
Administrative data
- Endpoint:
- adsorption / desorption: screening
- Remarks:
- other: adsorption/desorption screening test
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- December 2004
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- soil
Test material
- Reference substance name:
- Ethyl 3-((1-(4-methylamino-3-nitrophenyl)methanoyl)pyridin-2-yl-amino)propionate
- EC Number:
- 454-450-1
- EC Name:
- Ethyl 3-((1-(4-methylamino-3-nitrophenyl)methanoyl)pyridin-2-yl-amino)propionate
- Cas Number:
- 429659-01-8
- Molecular formula:
- C18 H20 N4 O5
- IUPAC Name:
- ethyl 3-{1-[4-(methylamino)-3-nitrophenyl]-N-(pyridin-2-yl)formamido}propanoate
- Test material form:
- solid: particulate/powder
Constituent 1
- Radiolabelling:
- no
Results and discussion
Adsorption coefficient
- Sample No.:
- #1
- Type:
- log Koc
- Value:
- 2.46 dimensionless
- Temp.:
- 20 °C
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Followin the criteria reported in the method C19 "Estimation of the adsorption coefficient (Koc) on soil and on sewage using HPLC", BIBR 1048 Manamide can be considered not completely adsorbed in the soil.
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