Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-592-6 | CAS number: 143-22-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
2-(2-(2-butoxyethoxy)ethoxy)ethanol does not have a high potential for adsorption to soil due to its fully miscible with water.
The Koc of triethylene glycol monobutyl ether or (2-(2-(2-butoxyethoxy)ethoxy)ethanol) can be estimated to be 10 . According to a classification scheme, this estimated Koc value suggests that triethylene glycol monobutyl or (2-(2-(2-butoxyethoxy)ethoxy)ethanol) ether is expected to have very high mobility in soil.
The estimated Soil Adsorption Coefficient was 10 L/kg measured by calculation from EPI SuiteTM v4.0 Program. This is Exposure Assessment Tools and Models made from EPA (Environmental Protection Agency
These results suggest that the 2-(2-(2-butoxyethoxy)ethoxy)ethanol has high soil mobility in soil .
KOCWIN Program (v2.00) Results:
==============================
SMILES : O(CCOCCOCCO)CCCC
CHEM : Ethanol, 2- 2-(2-butoxyethoxy)ethoxy -
MOL FOR: C10 H22 O4
MOL WT : 206.28
--------------------------- KOCWIN v2.00 Results ---------------------------
Koc Estimate from MCI:
---------------------
First Order Molecular Connectivity Index ........... : 6.914
Non-Corrected Log Koc (0.5213 MCI + 0.60) .......... : 4.2042
Fragment Correction(s):
1 Aliphatic Alcohol (-C-OH) ........... : -1.3179
3 Ether, aliphatic (-C-O-C-) .......... : -2.6148
Corrected Log Koc .................................. : 0.2715
Over Correction Adjustment to Lower Limit Log Koc ... : 1.0000
Estimated Koc: 10 L/kg <===========
Koc Estimate from Log Kow:
-------------------------
Log Kow (Kowwin estimate) ......................... : 0.02
Non-Corrected Log Koc (0.55313 logKow + 0.9251) .... : 0.9362
Fragment Correction(s):
1 Aliphatic Alcohol (-C-OH) ........... : -0.4114
3 Ether, aliphatic (-C-O-C-) .......... : -0.2718
Corrected Log Koc .................................. : 0.2529
Estimated Koc: 1.79 L/kg <===========
Key value for chemical safety assessment
- Koc at 20 °C:
- 10
Additional information
Adsorption
According to “ANNEX IX- STANDARD INFORMATION REQUIREMENTS FOR SUBSTANCES MANUFACTURED OR IMPORTED IN QUANTITIES OF100TONNESOR MORE, an adsorption study need not be conducted if:
— based on the physicochemical properties the substance can be expected to have a low potential for adsorption (e.g. the substance has a low octanol water partition coefficient), or
— the substance and its degradation products decompose rapidly.
Octanol/Water Partition Coefficient of 2-(2-(2-butoxyethoxy)ethoxy)ethanol is low(log Kow = 0.51)
2-(2-(2-butoxyethoxy)ethoxy)ethanol does not have a high potential for adsorption to soil due to its fully miscible with water. The Koc of triethylene glycol monobutyl ether or (2-(2-(2-butoxyethoxy)ethoxy)ethanol) can be estimated to be 10 . According to a classification scheme, this estimated Koc value suggests that triethylene glycol monobutyl or (2-(2-(2-butoxyethoxy)ethoxy)ethanol) ether is expected to have very high mobility in soil.
The estimated Soil Adsorption Coefficient was 10 L/kg measured by calculation from EPI SuiteTM v4.0 Program. This is Exposure Assessment Tools and Models made from EPA (Environmental Protection Agency
These results suggest that the 2-(2-(2-butoxyethoxy)ethoxy)ethanol has high soil mobility and does not have a high potential for adsorption to soil
KOCWIN Program (v2.00) Results:
==============================
SMILES : O(CCOCCOCCO)CCCC
CHEM : Ethanol, 2- 2-(2-butoxyethoxy)ethoxy -
MOL FOR: C10 H22 O4
MOL WT : 206.28
--------------------------- KOCWIN v2.00 Results ---------------------------
Koc Estimate from MCI:
---------------------
First Order Molecular Connectivity Index ........... : 6.914
Non-Corrected Log Koc (0.5213 MCI + 0.60) .......... : 4.2042
Fragment Correction(s):
1 Aliphatic Alcohol (-C-OH) ........... : -1.3179
3 Ether, aliphatic (-C-O-C-) .......... : -2.6148
Corrected Log Koc .................................. : 0.2715
Over Correction Adjustment to Lower Limit Log Koc ... : 1.0000
Estimated Koc: 10 L/kg <===========
Koc Estimate from Log Kow:
-------------------------
Log Kow (Kowwin estimate) ......................... : 0.02
Non-Corrected Log Koc (0.55313 logKow + 0.9251) .... : 0.9362
Fragment Correction(s):
1 Aliphatic Alcohol (-C-OH) ........... : -0.4114
3 Ether, aliphatic (-C-O-C-) .......... : -0.2718
Corrected Log Koc .................................. : 0.2529
Estimated Koc: 1.79 L/kg <===========
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.