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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Endpoint:
dissociation constant
Type of information:
other: online database
Adequacy of study:
key study
Study period:
unknown
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data obtained from an authoritative secondary source

Data source

Reference
Reference Type:
review article or handbook
Title:
Handbook of Chemistry and Physics. 69th ed. Boca Raton, FL: CRC Press Inc.,
Author:
Weast, R.C. (ed.)
Year:
1988
Bibliographic source:
http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
No data information from handbook source
GLP compliance:
no
Remarks:
Handbook and peer reviewed secondary source

Test material

Constituent 1
Chemical structure
Reference substance name:
2-pyridylamine
EC Number:
207-988-4
EC Name:
2-pyridylamine
Cas Number:
504-29-0
Molecular formula:
C5H6N2
IUPAC Name:
pyridin-2-amine

Results and discussion

Dissociation constant
No.:
#1
pKa:
ca. 6.82
Temp.:
20 °C
Remarks on result:
other: No other data information from handbook source

Applicant's summary and conclusion

Conclusions:
Information from the reliable handbook source indicates that the dissociation constant(pKa ) of 2-aminopyridine is 6.82 @ 20 deg C
Executive summary:

Information from the reliable handbook source indicates that the dissociation constant(pKa ) of 2-aminopyridine is 6.82 @ 20 deg C