Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

First-aid measures

Emergency measure - Inhalation: Remove to fresh air. If there is difficulty in breathing,
administer oxigen. If person is not breathing, artificial
respiration can be attempted. Seek medical attention.
Emergency measure - Eyes: Irrigate with large amounts of water for 15 minutes, seek
medical attention.
Emergency measure - Skin: Wash with water and soap. Seek medical attention.
Emergency measure - Ingestion: Seek immediate medical attention or transport to hospital
immediately.

Fire-fighting measures

Recommended extinguishing agent: To date there is no evidence that the substance is flammable
(see 3.1.00).

Fires may be extinguished with water, carbon dioxide, or dry
chemical powder. Fight fire from a safety distance; divert
runoff to a safe area.

Product arising from burning: None known.

Product determined by test: Y

Protective equipment: Wear full protective clothing and use self contained
breathing apparatus.

Accidental release measures

Emergency measures in case of spillage: Wear protecting clothes and gloves. Avoid generation and
inhalation of dust. Sweep up using clean tools and place
into sealed containers (for liquid spills, i.e. solutions,
use sand or other inhert adsorbents for taking up).

Handling and storage

Handling: Use in well ventilated areas, local exhaust ventilation and
careful use are recommended to minimize dust generation.
Protect eyes, skin and respiratory system; use approved
personal protection and gloves when handling. Wash
thouroughly after using.

Storage: Store in sealed unbreakable containers, protected from light
moisture and heat.

Packaging of the substance and or preparation: For 10-Deacetylbaccatin III, a multylayer sack is used, made
up of:

1) A polyester external layer

2) An aluminum layer

3) A nylon layer

4) An alimentary use polyethylene internal layer

2.5 Kg of product are packaged into each sack, which is then
sealed.

Each sack is placed inside a tin-plated steel container,
with hermetical closure and plastic seal.

Packaging is completed by introducing 1 or 2 containers (of
product from a same batch) inside "Kraft" type cardboard
drums (UN approved packaging material - 2 sizes are
available, for 1 or 2 unit packaging, with similar
characteristics).

Transport information

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Marine transport (UN RTDG/IMDG)

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Air transport (UN RTDG/ICAO/IATA)

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Special provisions / remarks
Remarks:
Transport code: UN 2811
Transport: The substance has been classified as follows: UN 2811 (TOXIC
SOLID, ORGANIC, N.O.S.), CLASS 6.1, PACKING GROUP III.

(This classification has been adopted for precaution,
although 10-Deacetylbaccatin III prooved to be harmless if
swallowed for laboratory animals, lacking data on effects on
man).
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Exposure controls / personal protection

Stability and reactivity

Danger other than fire: No other dangers identified.

Chemical reaction with water: None dangerous known.

The substance readily degrades in contact with strong bases.

Dust explosion: As for all organic powders, explosion hazard may exist if
dusts are released in presence of sparks, flames, static
electricity etc.

Dust explosion determined by test: N

Disposal considerations

Industry - Possibility of recovery/recycling: It is possible to recovery the used substance.

Industry - Possibility of neutralisation: By using strong bases.

Industry - Possibility of destruction: controlled discharge: None specific known.

Industry - Possibility of destruction - incineration: Yes.

Industry - Possibility of destruction - water purification: Yes.

Industry - Possibility of destruction - other: --