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Diss Factsheets
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EC number: 459-330-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 05/Jul/04 - 12/Oct/04
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- method to determine freezing temperature
- Specific details on test material used for the study:
- Asahiklin AE-3000, molecular weight 200.7
CAS 406-78-0
Clear colourless liquid
Batch 50407070
Purity: 99.985%
The test substance was stored in a refrigerator in the dark under stable conditions
The test substance expiry date was the 07 July 2005 - Key result
- Melting / freezing pt.:
- < -81 °C
- Conclusions:
- The freezing temperature for 1,1,2,2-tetrafluoroethyl-2,2,2-trifluoroethyl ether was determined to be < -81°C
- Executive summary:
An experiment was carried out to determine the freezing point of 1,1,2,2-tetrafluoroethyl-2,2,2-trifluoroethyl ether. Three test tubes were filled with 5mL of the test substance and stored at temperatures of 4.1/ 5.1°C, -26.0/ -24.3°C
and -82.6/ -81.4°C respectively. After storage for 2 hours at these temperatures, 1,1,2,2-tetrafluoroethyl-2,2,2-trifluoroethyl ether remained a clear, colourless liquid with no indication of solidification or the freezing process. The freezing temperature of 1,1,2,2-tetrafluoroethyl-2,2,2-trifluoroethyl ether was therefore deemed to be <81°C and resultantly no main study was performed.
Reference
The freezing temperature is defined as the temperature at which the phase transition from liquid to solid state takes place at normal atmospheric pressure. This temperature ideally corresponds to the solidification or freezing temperature.
The table below summaries the temperatures and the visual observations during the preliminary screening test:
Temperature range during storage [°C] |
Test substance appearance after 1 hour | Test substance appearance after an additional 1 hour period |
4.1 to 5.1 |
Clear colourless liquid | Clear colourless liquid |
-26.0 to -24.3 | Clear colourless liquid | Clear colourless liquid |
-82.6 to -81.4 | Clear colourless liquid | Clear colourless liquid |
Description of key information
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -81 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.