Registration Dossier
Registration Dossier
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EC number: 200-842-0 | CAS number: 75-12-7
Toxicity to other above-ground organisms
Administrative data
- Endpoint:
- toxicity to other above-ground organisms
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Publication mostly in Japanese, but basic data comprehensible (abstract available in English)
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicity of agrochemicals to freshwater|organisms
- Author:
- Nishiuchi Y
- Year:
- 1 984
- Bibliographic source:
- CIII. Solvents. Suisan Zoshoku 32(2), 115-119.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Formamide
- EC Number:
- 200-842-0
- EC Name:
- Formamide
- Cas Number:
- 75-12-7
- Molecular formula:
- CH3NO
- IUPAC Name:
- formamide
- Details on test material:
- - Name of test material (as cited in study report): Formamide
Constituent 1
Test substrate
- Vehicle:
- no
Test organisms
- Test organisms (species):
- other: tadpoles of frog Rana bravipodosa porosa
Study design
- Total exposure duration:
- 48 h
Test conditions
- Test temperature:
- 25 °C
- Details on test conditions:
- The toxicity of formamide used in preparations of agrochemicals was tested by determination of the LC50 (median lethal concentration) on frogs.
- test organisms: tadpoles of Rana bravipoda porosa
- mean length: 3.0 cm
- mean weight: 0.45 g
- test vessels: 200 ml beakers (9 x 9 cm)
- No. of tadpoles per test vessel: 10
- replicates: 2 (the experiment was repeated)
- observations: mortality after 3, 6, 12, 24 and 48 h
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 3 h
- Dose descriptor:
- LC50
- Effect conc.:
- 13 000
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 4 300
Any other information on results incl. tables
Effect values (mg/L):
Time: 3 h
6 h 12 h 24 h 48 h
LC50: 13000 8500 5800 4800 4300
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
