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EC number: 952-026-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 30 April 2021 - May 2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes
- Type of method:
- flask method
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source (i.e. manufacturer or supplier): Imerys
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature, in the dark - Key result
- Water solubility:
- 10.5 mg/L
- Conc. based on:
- element
- Remarks:
- Calcium
- Incubation duration:
- 24 h
- Temp.:
- 20 °C
- pH:
- 10.2
- Remarks on result:
- other: Range: 10.5 to 48.4 mg/L at 20.0 ± 0.5 ºC
- Key result
- Water solubility:
- 4.7 mg/L
- Conc. based on:
- element
- Remarks:
- Silicon
- Incubation duration:
- 24 h
- Temp.:
- 20 °C
- pH:
- 10.2
- Remarks on result:
- other: Range: 4.70 to 33.1 mg/L at 20.0 ± 0.5 ºC
- Key result
- Water solubility:
- 10.7 mg/L
- Conc. based on:
- element
- Remarks:
- Calcium
- Incubation duration:
- 48 h
- Temp.:
- 20 °C
- pH:
- 9.6
- Remarks on result:
- other: Range: 10.5 to 48.4 mg/L at 20.0 ± 0.5 ºC
- Key result
- Water solubility:
- 5.17 mg/L
- Conc. based on:
- element
- Remarks:
- Silicon
- Incubation duration:
- 48 h
- Temp.:
- 20 °C
- pH:
- 9.6
- Remarks on result:
- other: Range: 4.70 to 33.1 mg/L at 20.0 ± 0.5 ºC
- Key result
- Water solubility:
- 48.4 mg/L
- Conc. based on:
- element
- Remarks:
- Calcium
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- pH:
- 8.5
- Remarks on result:
- other: Range: 10.5 to 48.4 mg/L at 20.0 ± 0.5 ºC
- Key result
- Water solubility:
- 33.1 mg/L
- Conc. based on:
- element
- Remarks:
- Silicon
- Incubation duration:
- 72 h
- Temp.:
- 20 °C
- pH:
- 8.5
- Remarks on result:
- other: Range: 4.70 to 33.1 mg/L at 20.0 ± 0.5 ºC
- Details on results:
- Preliminary Test
The preliminary estimate of the water solubility at 20.0 ± 0.5 °C is shown in Table 2 below.
Definitive Test
The mean counts per second relating to the standard and sample solutions are shown in the
Table 3 below.
The concentration (mg/L) of test item in the sample solutions is shown in Table 4 below. - Conclusions:
- The water solubility of the test item has been determined to be over the ranges of 10.5 to 48.4 mg/L for calcium and 4.70 to 33.1 mg/L for silicon in solution at 20.0 ± 0.5 °C.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- Testing was conducted between 10 March 2010 and 26 March 2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Water solubility:
- 3.7 mg/L
- Temp.:
- 20 °C
- pH:
- 3
- Conclusions:
- The water solubility of the test material has been determined to be less than or equal to 3.7 mg/L of solution at 20.0± 0.5°C. The test material has been determined to be essentially insoluble in water.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Guideline study, non GLP
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- flask method
- Key result
- Water solubility:
- 11 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 7
- Details on results:
- Solubility increased with time, but did not exceed 15 %.
- Conclusions:
- Slightly soluble (0.1-100 mg/L)
Referenceopen allclose all
Table 2 Preliminary Results
Concentration (mg/L) | Solution pH | |
Calcium | Silicon | |
28.0 | 11.7 | 10.4 |
Table 3 Counts Per Second
Solution | Mean Counts per Second | ||
Calcium | Silicon | Internal Standard | |
Matrix Blank | 438.69 | 2458.41 | 28727.56 |
Standard 1.00 mg/L | 10492.73 | 81901.27 | 29740.84 |
Standard 2.51 mg/L | 25864.18 | 201543.83 | 29651.86 |
Standard 5.02 mg/L | 50375.18 | 404143.70 | 29720.91 |
Standard 10.0 mg/L | 92707.28 | 739154.23 | 28243.21 |
Standard 10.0 mg/L | 90442.60 | 720630.05 | 27035.42 |
Standard 15.1 mg/L | 127931.33 | 1026086.41 | 26563.14 |
Standard 20.1 mg/L | 159899.18 | 1259745.08 | 24849.67 |
Matrix blank | 404.02 | 2443.64 | 25837.71 |
Sample 1A | 46579.16 | 169132.28 | 26057.00 |
Sample 1B | 44064.21 | 167083.56 | 26048.19 |
Sample 2A | 44228.87 | 178279.61 | 25425.08 |
Sample 2B | 46331.05 | 182269.63 | 25750.96 |
Sample 3A | 197974.19 | 1069064.05 | 25445.05 |
Sample 3B | 191535.11 | 1045135.00 | 24662.64 |
Table 4 Results
Sample Number | Time Shaken at ~ 30oC (hours) | Concentration (mg/L) | Solution pH | |
Calcium | Silicon | |||
1 | 24 | 10.5 | 4.70 | 10.2 |
2 | 48 | 10.7 | 5.17 | 9.6 |
3 | 72 | 48.4 | 33.1 | 8.5 |
The counts per second relating to the standard and sample solutions are shown in table 2.
Table 2:
Solution |
Counts per second |
Matrix blank |
4.005 x 105 |
Standard 1.0 x 10-2mg/L |
4.181 x 105 |
Standard 5.0 x 10-2mg/L |
4.395 x 105 |
Standard 0.10 mg/L |
4.955 x 105 |
Standard 0.10 mg/L |
4.900 x 105 |
Standard 0.50 mg/L |
8.659 x 105 |
Standard 1.00 mg/L |
1.368 x 106 |
Sample 1A |
1.082 x 106 |
Sample 1B |
1.115 x 106 |
Sample 2A |
1.850 x 106 |
Sample 2B |
1.790 x 106 |
Sample 3A |
1.383 x 106 |
Sample 3B |
1.370 x 106 |
The concentration (g/L) of test material in the sample solutions is shown in table 3:
Table 3:
Sample number |
Time shaken at ~30°C (hours) |
Time equilibrated at 20°C (hours) |
Concentration (g/L) |
Solution pH |
1 |
24 |
24 |
1.91 x 10-3 |
3.0 |
2 |
48 |
24 |
3.87 x 10-3 |
3.1 |
3 |
72 |
24 |
2.66 x 10-3 |
3.0 |
Discussion:
The preliminary test was considered unnecessary in this instance as the test material was anticipated to be essentially insoluble in water.
The linearity of the detector response with respect to the concentration was assessed over the concentration range of 0 to 0.400 mg/L. This was satisfactory with a correlation coefficient of 0.999 being obtained.
The results for samples 1 to 3 were somewhat variable and indicated no trend. However, a review of the chemical formula of the test material indicated that the above solutions would be essentially stable towards degradation, etc. Consequently, the variability in the results was considered to be due to non-uniformity of the test material as opposed to any issues with the test.
The highest result determined (sample) 2 has been given as a limit value for environmental assessment purposes.
Description of key information
The water solubility of the test material has been determined to be 10.5 and 10.7 mg/L for calcium and 4.70 and 5.17 mg/L for silicon. These represent the 24 and 48 hour shaking times.
The test material has been determined to be essentially poorly soluble in water.
Key value for chemical safety assessment
Additional information
Results are based on a key study performed to GLP and OECD guideline 105 (Fox 2021)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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