Registration Dossier
Registration Dossier
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EC number: 485-390-4 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The Acute Immobilisation of the registered substance to Daphnia magna (STRAUS) was determined according to OECD Guideline 202 (2004). The EL50 (48h) was determined as 4.01 mg/L. However, the determined EL50 is far above the solubility limit of the substance. Therefore, this result is considert not relevant for classification.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 4.01 mg/L
Additional information
The Acute Immobilisation of the registered substance to Daphnia magna (STRAUS) was determined according to OECD Guideline 202 (2004). The study was conducted with 6 loading levels of the water accomodated fraction ranging from 0.625 to 20.0 mg/L in a geometric series with a dilution factor of 2 under static conditions over a period of 48 h. All loading levels and the control were analytically verified via GC-MS after 0 h (new media) and 48 h (old media). All effect values are given based on the loading levels of the water accommodated fraction.
The EL10- and EL50-values after 24 and 48 h were calculated by sigmoidal dose-response regression. A reference test was carried out with potassium dichromate as reference item. The EC50-value of the reference item at 1.67 mg/L after 24 h was within the prescribed concentration range of 1.0 - 2.5 mg/L according to AQS P 9/2 (05/1996) for daphnids clone 5 cultured in Elendt M4
medium (DIN 38412 - L 30). Water quality parameters pH-value and dissolved oxygen concentration were determined to be within the acceptable limits. The validity criteria of the test guideline were fulfilled.
The EL50 (48h) was determined as 4.01 mg/L. (Cognis, 2006)
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