Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 226-122-6 | CAS number: 5285-60-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 10 April 2018 to 20 June 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Version / remarks:
- 2016
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7200 (Melting Point / Melting Range)
- Version / remarks:
- 1998
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- differential scanning calorimetry
- Key result
- Atm. press.:
- >= 1 014 - <= 1 024 hPa
- Remarks on result:
- other: Glass transition point: -45.6°C. The substance has no melting/freezing temperature between 25°C and -90°C.
- Conclusions:
- A glass transition temperature of -45.6°C was determined. The substance has no melting/freezing temperature between 25°C and -90°C. The boiling temperature was determined to be 424.8°C (at 1019 ± 5 hPa).
- Executive summary:
Differential Scanning Calorimetry was performed to determine the melting and boiling temperature. The experiments were based on EC A.1, OECD 102 and OPPTS 830.7200 (melting temperature) and on EC A.2, OECD TG 103 and OPPTS 830.722 (boiling temperature). GLP-study.
The liquid substance has no melting/freezing temperature between 25°C and -90°C. DSC showed glass transition. From duplicate measurements a mean glass transition temperature was determined to be -45.6°C.
From two DSC experiments, the mean boiling temperature was determined to be 424.8°C (at 1019 ± 5 hPa).
Reference
DSC EXPERIMENT 1
During cooling, a glass transition was observed between -80°C and -40°C. During heating, a glass transition was observed between -50°C and -25°C. The inflection point of the glass transition was -45.675°C. An endothermic peak was observed starting at 300°C. After the experiment, a colourless residue remained in the sample container.
DSC EXPERIMENT 2
In order to investigate the endothermic peak observed from 300°C, Experiment 2 was stopped at 500°C. The inflection point of the glass transition was -45.425°C. The extrapolated onset temperature of the endothermic peak was 424.540°C. After the experiment it was observed that the test item had evaporated from the sample container. DSC curve during heating: see illustration below.
DSC EXPERIMENT 3
In order to further investigate the endothermicpeak, a higher heating rate of 50°C/minute was used in Experiment 3. The extrapolated onset temperature was 426.160°C. The endothermic peak had not shifted to significantly higher temperatures. It demonstrated that boiling of the test item caused the endothermic effect. After the experiment it was observed that the test item had evaporated from the sample container.
DSC EXPERIMENT 4
Experiment 4 was performed to determine the duplicate boiling temperature. The extrapolated onset of the boiling peak was 424.981°C. After the experiment it was observed that the test item had evaporated from the sample container.
DATA HANDLING
-The glass transition temperature was determined as the mean inflection point of Experiment 1 and Experiment 2.
-The boiling temperature was evaluated from the DSC curve as the extrapolated onset temperature of the endothermic boiling peak: mean of Experiment 2 (424.540°C) and Experiment 4 (424.981°C).
Description of key information
Glass transition temperature: -45.6°C (EC A.1, OECD 102, OPPTS 830.7200: DSC)
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -45.6 °C
Additional information
no melting/freezing temperature between 25°C and -90°C
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.