Registration Dossier
Registration Dossier
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EC number: 250-151-3 | CAS number: 30364-51-3
Endpoint summary
Administrative data
Description of key information
Additional information
Sodium N-methyl-N-(1-oxotetradecyl)aminoacetate (CAS 30364 -51-3) is a mono-constituent salt characterized by a water solubility of 360 g/L (25 °C, pH 8.8), a calculated vapour pressure of 0.0000749 Pa (25 °C, MPBPWIN v1.43), a calculated log Kow of 1.35 (KOWWIN v1.68) and a calculated log D of 4.18 at pH 4, 1.52 at pH 7 and 0.63 at pH 9 (SPARC v4.6). Furthermore, the substance is readily biodegradable (85.2% in 28 d, OECD 301 B, activated sludge) based on a standard biodegradation study with a structurally and chemically related source substance. The estimated log Koc (ChemProp v6.5, Franco, Fu & Trapp model for ionisable substances) is 2.2 – 2.5 at pH 7, indicating a low potential for adsorption to particles present in soil and sediment.
Thus, if released into the environment, the substance is expected to mainly distribute into the aquatic compartment based on the available data. Furthermore, the substance is expected to be mobile in water at environmentally relevant pH. However, it will not persist in the environment due to ready biodegradability. According to the Guidance on information requirements and chemical safety assessment, Chapter R.7b, readily biodegradable substances can be expected to undergo rapid and ultimate degradation in most environments, including biological sewage treatment plants (ECHA, 2016). Abiotic degradation via hydrolysis or phototransformation in air is not a relevant environmental fate pathway based on the ready biodegradability and low vapour pressure of the substance, respectively.
Overall, the bioavailability of the substance to aquatic organisms is expected to be low due to low discharge into the environment (owing to extensive biodegradation in conventional STPs) on the one hand and minimal persistence due to ready biodegradability on the other hand. The potential for bioaccumulation is expected to be low based on a log Kow of 1.35, a log D of 1.52 at the environmentally relevant pH of 7 and the estimated BCF values (BCFBAF v3.01), which are clearly < 2000 L/kg wet-wt.
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