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EC number: 244-955-3 | CAS number: 22397-58-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 28 Oct - 03 Nov 2014
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION:
The test solution was prepared in the concentration 100 m/L in test medium. Five concentrations were preped by dilutions in water. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: water flee (D. magna strauss)
- Source: in-house culture
- Age at study initiation: 6-24h
- Method of breeding: kept in reconstituted water, water changed 3 times per week, fed with green alga
- Feeding during test: none - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Post exposure observation period:
- none
- Hardness:
- 140-250 mg CaCO3/L
- Test temperature:
- 20.0 - 20.1 °C
- pH:
- Control: 7.79 - at test initiation; 7.95 - at test end
Test samples: 7.42 - at test initiation; 7.52 - at test end - Dissolved oxygen:
- Control: 6.18 mg/L - at test initiation; 6.64 mg/L - at test end
Test samples: 6.0 mg/L - at test initiation; 6.21 mg/L - at test end - Nominal and measured concentrations:
- 0, 3.21, 7.06, 15.53, 34.18, 75.19 mg/L (nominal for tested product)
- Details on test conditions:
- TEST SYSTEM
- Test vessel: 500 mL glass beakers
- No. of organisms per vessel: 5
- No. of vessels per concentration (replicates): 4
- No. of vessels per control (replicates): 4
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: deionised water with additions of salts.
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: 16 h light / 8 h dark
- Light intensity: not stated
EFFECT PARAMETERS MEASURED (with observation intervals if applicable): mobility after 24 and 48 h
TEST CONCENTRATIONS
- Range finding study
- Test concentrations: 0, 0.01, 0.10, 1.0, 10, 100 mg/L - Reference substance (positive control):
- no
- Duration:
- 48 h
- Dose descriptor:
- LC50
- Effect conc.:
- 0.948 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mobility
Reference
Table 1. Number of immobile Daphniae at 24 and 48 hours:
Test concentration [mg/L] | No. of immobile Daphniae | |
at 24 h | at 48 h | |
0 | 0/20 | 0/20 |
3.21 | 5/20 | 11/20 |
7.06 | 5/20 | 12/20 |
15.53 | 5/20 | 19/20 |
34.18 | 10/20 | 20/20 |
75.18 | 19/20 | 20/20 |
Description of key information
48h EC50 (Daphnia magna, mobility) = 0.948 mg a.i./L (nominal concentration, OECD 202)
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.948 mg/L
Additional information
One short-term toxicity test with aquatic invertebrates is available for C12-14 AS Zn. The GLP study (Z&S, 2014) was performed with Daphnia magna according to OECD 202 guideline. Daphnids were exposed to several test concentrations: 0, 3.21; 7.06; 15.53; 34.18; 75.19 mg product/L (nominal values). The tested product had a purity of 26.6% and the remaining was water. The TOC analysis proved that the test concentrations are stable over time. Since no other analytical measurements of the test substance were performed, the results are based on the nominal concentrations. The number of immobile organisms was evaluated after 24 and 48 hours. The 48-h EC50 value was 3.575 mg product/L and 0.948 mg a.i./L (nominal concentration).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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