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Diss Factsheets
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EC number: 608-408-6 | CAS number: 29736-24-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- other: occupational medical statement
- Adequacy of study:
- supporting study
- Study period:
- 1976 -2010
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Non GLP-guideline study. Read-across from an occupational Medical Statement: Effects of BRUGGOLEN FF6 to exposed workers. Similarity of BLANCOLEN HP and BLANCOLEN HP BRUGGOLITE FF6 is a multi-constituent substance composed of • Disodium hydroxysulfinateacetate • Disodium hydroxysulfonateacetate • Sodium sulphite (as impurity) BLANCOLEN HP is the mono-constituent substance • Disodium hydroxysulfonateacetate During the manufacturing of BRUGGOLITE FF6 (the desired molecule is disodium hydroxysulfinate-acetate) the formation of disodium hydroxysulfonateacetate cannot be avoided. Sodium sulphite is an impurity resulting from the starting material. BLANCOLE HP can be obtained by a similar reaction as a mono-constituent substance. Especially in aqueous media, disodium hydroxysulfinateacetate of BRUGGOLITE FF6 is easily oxidized; the primarily resulting product is disodium hydroxysulfonateacetate. Therefore, practically no significant differences will occur between testing of BRUGGOLITE FF6 and BLANCOLEN HP in aqueous systems if any contributions of sodium sulphite to the result can be neglected. Moreover disodium hydroxysulfinateacetate is the stronger reducing agent and is expected to induce more severe effects compared to the hydroxysulfonateacetate.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
- Objective of study:
- other: corrosive/ irritation effects... (see attached file)
- Principles of method if other than guideline:
- Occupational Medical Assessment
- GLP compliance:
- no
Test material
Reference
- Name:
- Unnamed
- Type:
- Constituent
- Details on test material:
- Test material is BRUGGOLITE FF6
Test animals
- Species:
- human
- Sex:
- male
Administration / exposure
- Route of administration:
- inhalation: dust
- Vehicle:
- unchanged (no vehicle)
- Duration and frequency of treatment / exposure:
- not applicable
Doses / concentrations
- Remarks:
- Doses / Concentrations:
not applicable
- No. of animals per sex per dose / concentration:
- not applicable
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.