Registration Dossier
Registration Dossier
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EC number: 263-058-8 | CAS number: 61789-40-0
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to fish, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Justification for type of information:
- Data is from secondry source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study)
- GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Vehicle:
- not specified
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Test type:
- other: Static-renewal
- Water media type:
- freshwater
- Total exposure duration:
- 28 h
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.16 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 28 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 0.5 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The no effect concentration (NOEC) and low effect concentration (LOEC) value of test chemical after 28 days exposure was observed to be 0.16 mg/l and 0.5 mg/l respectively.
- Executive summary:
An experiment was conducted to determine the long term toxicity of test chemical by using OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study). In this study test organism used was Oncorhynchus mykiss. The no effect concentration (NOEC) and low effect concentration (LOEC) after 28 days was observed to be 0.16 mg/l and 0.5 mg/l respectively. By considering the no effect concentration (NOEC) value test chemical is considered to be toxic and can be classified as aquatic chronic 3 for long term toxicity to fish.
Reference
Description of key information
An experiment was conducted to determine the long term toxicity of test chemical by using OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study). In this study test organism used was Oncorhynchus mykiss. The no effect concentration (NOEC) and low effect concentration (LOEC) after 28 days was observed to be 0.16 mg/l and 0.5 mg/l respectively. By considering the no effect concentration (NOEC) value test chemical is considered to be toxic and can be classified as aquatic chronic 3 for long term toxicity to fish.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.16 mg/L
Additional information
An experiment was conducted to determine the long term toxicity of test chemical by using OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study). In this study test organism used was Oncorhynchus mykiss. The no effect concentration (NOEC) and low effect concentration (LOEC) after 28 days was observed to be 0.16 mg/l and 0.5 mg/l respectively. By considering the no effect concentration (NOEC) value test chemical is considered to be toxic and can be classified as aquatic chronic 3 for long term toxicity to fish.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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