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EC number: 206-460-0 | CAS number: 345-35-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- November 21, 2019 - March 18, 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential thermal analysis
Test material
- Reference substance name:
- Reference substance 001
- Cas Number:
- 345-35-7
- Test material form:
- liquid
Constituent 1
- Specific details on test material used for the study:
- None
Results and discussion
Boiling point
- Key result
- Boiling pt.:
- >= 160 - <= 163 °C
- Remarks on result:
- other: Measured under atmospheric conditions.
Any other information on results incl. tables
A DSC measurement with the test item in an aluminium crucible with a hole showed an exothermal effect starting at approximately 115 °C. No further endothermal or exothermal effects were observed up to the final temperature (500 °C). The mass loss after the DSC measurements amounted to 51 %.
The results of the DSC measurements are summarized in Table 3.
Table 3: Boiling point (DSC measurement in open aluminium crucibles)
Ident No. | Test item / mg | Starting temperature / °C | Final test temperature / °C | Temperature range (endo-thermal) / °C | Onset (boiling) / °C | Crucible | Observations after the measurement |
38916 | 8.08 | 25 | 500 | -- | -- | Aluminium with a hole | Black residue in the crucible, mass loss: 51 % |
As in the determination of the vapour pressure by dynamic method (see report No.:PS20190384-3) the test item was heated up to 166 °C without any apparent decomposition, it was assumed that the test item reacted with the aluminium of the crucible. This observation was in accordance with the information in chapter 10.3 of the safety data sheet (SDS-Number 122000001459, 2-Fluorbenzylchlorid; version 8.0) stating that the test item reacts with many metals.
Therefore, two DSC measurements were performed in open glass crucibles as follows:
The test item was cooled down to -80 °C with a cooling rate of 1 K/min, -80 °C were kept for 60 min and afterwards the test item was heated up to 300 °C with a heating rate of 10 K/min. During heating up, the measurements showed an endothermal effect (boiling) after melting in the temperature range of 100 °C to 195 °C. The onset temperature (see Table 2) was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline.
The results of the DSC measurements in open glass crucibles are summarized in Table 4.
Table 4: Boiling point (DSC measurements in open glass crucibles)
Ident No. | Test item / mg | Starting temperature / °C | Final test temperature / °C | Temperature range (endo-thermal) / °C | Onset (melting) / °C | Crucible | Observations after the measurement |
39070 | 13.21 | -80 | 300 | 100 – 190 | 160.63 | Glass (open) | Mass loss 100 % |
39072 | 13.51 | -80 | 300 | 100 – 195 | 162.10 | Glass (open) | Mass loss 100 % |
A decomposition of the test item was not observed in open class crucibles up to 300 °C.
The test item had a boiling range under atmospheric conditions of 160 °C to 163 °C.
Applicant's summary and conclusion
- Executive summary:
The test item had a boiling range under atmospheric conditions of 160 °C to 163 °C.
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