Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 226-214-6 | CAS number: 5328-37-0
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Conclusion on Persistance: not vP and not P
In a Ready Biodegradability Test according to OECD Guideline 301 D, EU-Method C.4-E and EPA OPPTS 835.3110, the test item reached a biodegradation rate of 85.7 % biodegradation (based on its ThODNH4) on day 28. The 10-day window criterion for ready biodegradation was unequivocally fulfilled as more than 60 % biodegradation of the test item (78.3 %, based on its ThODNH4) was observed on the fifth day of the test. (see IUCLID section 5.2.1). Therefore, the test item is regarded to be in the 10-d-window and after 28 days readily biodegradable. Consequently, the substance is not considered to be persistent (P) or very persistent (vP).
Conclusion on Bioaccumulation: not vB and not B
In a study according to OECD TG 107 and EU Method A.8 the log Pow of the test item was determined to be -2.8 at 20 °C (see IUCLID section 4.7). This result is below the threshold value for bioaccumulative potential of log Pow > 4.5 as cited in the ECHA Guidance on Information Requirements and Chemical Safety Assessment, Part C: PBT/vPvB assessment (Version 3.0, June 2017). Thus, the substance is not considered to be very bioaccumulative (vB) or bioaccumulative (B).
Conclusion on Toxicity: not T
The criterion for toxicity is not fulfilled, since the EC10 for aquatic organisms is >= 0.01 mg/L (the 72-h EC10 (growth rate) for Raphidocelis subcapitata was determined to be > 100 mg/L; see IUCLID section 6.1.5); and the substance does not meet the criteria for classification as carcinogenic (category 1A or 1B), germ cell mutagenic (category 1A or 1B), or toxic for reproduction (category 1A,1C,or 2) according to Regulation EC No 1272/2008; and there is no evidence of chronic toxicity as identified by the substance meeting the critaria for classification: specific target organ toxicity after repeated exposure (STOT RE category 1 or 2) according to Regulation 1272/2008.
Overall conclusion on PBT and vPvB
Based on the available information, the substance is not PBT / vPvB according to Regulation (EC) 1907/2006.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
