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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 238-015-1 | CAS number: 14171-00-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance has a low potential for bioaccumulation based on log Kow <=3
- other:
- Justification for type of information:
- Substance is highly water soluble and is considered to be readily biodegradable
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
- Endpoint:
- partition coefficient
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Remarks:
- The substance is surface active and has a mixed molecular weight. As such, it is not possible to make a reliable estimate of the partition coefficient. However, the substance is miscible in water and there is high confidence that the partition coefficient is < 1.
- Justification for type of information:
- Estimation based on miscibility in water and confirmed by basic modelling
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The physicochemical properties of the substances were assessed, including consideration of solublity in water and organic solvents.
The EPISuite model was also used. - GLP compliance:
- not specified
- Type of method:
- estimation method (solubility ratio)
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Sodium salt used for modelling assessment as amine counter ions invalidated the methods
- Type:
- log Pow
- Partition coefficient:
- < 1
- pH:
- ca. 7
- Remarks on result:
- other: Modelled based on neutral conditions
- Conclusions:
- Being miscible in water and poorly soluble in non-polar solvents, the partition coefficient can be reliably assessed to be < 1
The KOA WIN method (EPISuite) suggests Log Kow ca 1.15 for the acid, with the sodium salt known to be more soluble in water providing a negative result.
Due to the potential dissociation properties, changing the pH may impact on these properties, although the acid form and salts are still significantly soluble in water.
- Reason / purpose for cross-reference:
- data waiving: supporting information
Reference
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Justification for type of information:
- Study performed on sodium salt.
The triethanolamine salt also dissociates and triethanolamine biodegradation has been well investigated - Reason / purpose for cross-reference:
- read-across: supporting information
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- not specified
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Duration of test (contact time):
- 28 d
- Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (CO2 evolution)
- Value:
- ca. 70
- Sampling time:
- 9 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- ca. 96
- Sampling time:
- 28 d
- Details on results:
- Two concentrations tested, but lower concentration (approx 10 mg/l C) gave a % degradation over over 100% and has been disregarded.
The higher concentration of approximately 30 mg/l C resulted in a plateau of about 100% degradation after day 22. The 10 day window was achieved.
The positive control group reached a plateau of about 80% after 22 days, but failed to reach the 60% in 10 day criteria. - Results with reference substance:
- The positive control group reached a plateau of about 80% after 22 days, but failed to reach the 60% in 10 day criteria.
- Validity criteria fulfilled:
- no
- Interpretation of results:
- readily biodegradable
- Executive summary:
There are obvious flaws in the testing, such as exceeding 100% for one of the concentrations tested and the poor performance of the positive control. However, earlier studies (albeit with less detail on methods and limited reporting) and estimations based on modelling and considering the class of substance suggests that the the substance is readily biodegradable.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.