2-hydroxycyclohepta-2,4,6-trienone

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

27 September 2016 to 20 February 2017

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

The measured vapour pressures are outside the measuring range of the vapour pressure balance. Nevertheless as the vapour pressure values above 1 Pa could be detected properly by the vapour pressure balance, the values can be used for the evaluation.

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

GLP compliance:

no

Type of method:

effusion method: vapour pressure balance

Key result

Temp.:

20 °C

Vapour pressure:

2 Pa

Key result

Temp.:

25 °C

Vapour pressure:

3.4 Pa

Key result

Temp.:

50 °C

Vapour pressure:

33 Pa

Transition / decomposition:

no

Thermal Stability results

In the temperature range of 40 - 70 °C an endothermic effect (melting), was observed. No further thermal effects were observed up to the maximum test temperature of 300 °C.

 

Effusion method: Vapour pressure balance results

The vapour pressure was measured in the temperature range of 27 to 58 °C. The measured vapour pressure values together with the measured temperatures are listed in the following table.

 

 Results of the Effusion method

No.	Temperature / °C	Vapour pressure / Pa
1	27	4.19 × 10^0
2	32	6.17 × 10^0
3	38	1.37 × 10^1
4	43	1.51 × 10^1
5	48	2.69 × 10^1
6	53	4.59 × 10^1
7	58	1.07 × 10^2

 

The measured vapour pressures are outside the measuring range (10 ^-3 to 1 Pa) of the vapour pressure balance. Nevertheless as the vapour pressure values above 1 Pa could be detected properly by the vapour pressure balance, the values can be used for the evaluation.

 

From the measured data points of the vapour pressure curve the constants A and B of the Antoine equation can be derived by regression of the data points to

A = 13.3737

B = -3830.91

 

The vapour pressure values of the test item calculated by interpolation and extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, according to Regulation EC No. 440/2008 Method A.4. Vapour Pressure and OECD Test Guideline 104 (2006) are shown in the table below.

 

Calculated vapour pressure values for 20, 25 and 50 °C

Temperature / °C	Vapour pressure / Pa
20	2.0 × 10^0
25	3.4 × 10^0
50	3.3 × 10^1

 

Final Results

The vapour pressure of the test item was calculated by interpolation and extrapolation of the measured vapour pressure curve for the temperatures 20, 25 and 50 °C, according to Regulation EC No. 440/2008 Method A.4. Vapour Pressure and OECD Test Guideline 104 (2006). The resulting vapour pressures are 2.0, 3.4 and 33 Pa, respectively.

Conclusions:

Vapour pressure values of 2.0 Pa (at 20 °C), 3.4 Pa (at 25 °C) and 33.0 Pa (at 50 °C) were determined for the test substance according to E.U. Method A.4.

Description of key information

Vapour pressure: 2.0 Pa at 20 °C, 3.4 Pa at 25 °C, and 33.0 Pa at 50 °C (EU Method A.4, effusion method: vapour pressure balance)

Key value for chemical safety assessment

Vapour pressure:

3.4 Pa

at the temperature of:

25 °C

Additional information

According to Regulation EC No. 440/2008 Method A.4, the vapour pressure values of the test item for the temperatures 20, 25 and 50 °C were calculated by extrapolation.

The measured vapour pressures were outside the measuring range of the vapour pressure balance. Nevertheless as the vapour pressure values above 1 Pa could be detected properly by the vapour pressure balance, the values were used for the evaluation.