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EC number: 211-064-6 | CAS number: 628-97-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Read across category
- Justification for type of information:
- See attached document in section 0"Categries" and section 13 "Assessment reports" for justification and rationale for category approach.
- Key result
- Water solubility:
- < 0.15 mg/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- ca. 6.4
- Conclusions:
- Based on the results from studies performed on source chemicals of the category, the water solubility of the source substances was defined to be less than 0.15 mg/L. According to the category approach, this water solubility value < 0.15 mg/L could be attributed to the target substance Ethyl palmitate. Hence, Ethyl palmitate was considered to have a low solubility in water.
Reference
Table 1: Results from key studies performed on the source substances of the category
Common name |
CAS |
Fatty acid chain length |
Type of alcohol |
MW |
Appareance |
Water Solubility |
Isopropyl myristate |
110-27-0 |
C14 |
Isopropanol |
270,46 |
Liquid |
Experimental result: <0.05 mg/L at 20 °C |
Isopropyl palmitate |
142-91-6 |
C16 |
Isopropanol |
298.51 |
Liquid |
no data |
Ethyl linoleate |
544 -35-4 |
C18:2 |
ethanol |
308,5 |
Liquid |
no data |
Ethyl oleate |
111-62-6 |
C18:1 |
ethanol |
310.52 |
Liquid |
no data |
Fatty acids, C16-18, butyl esters |
85408-76-0 |
C16-18 |
Butanol |
312.53 – |
Paste |
Experimental result: |
Fatty acids, C16-18 and C18-unsatured, isobutyl esters |
84988-79-4 |
C16-18, |
Isobutanol |
312.53 – |
Liquid |
Experimental result: |
Isopropyl isostearate |
68171-33-5 |
C18iso |
Isopropanol |
326.56 |
Liquid |
Experimental result: |
The physical-chemical properties of the category members are similar or follow a regular pattern over the category. Several members of the category have been tested for their water solubility. The tested substances represent different fatty acid chain lengths, C14, C16 and C18 or C18unsat.,combined with different alcohols, isopropanol, butanol or isobutanol.
Experimental results were obtained for several category members which all show water solubility less than 0.15 mg/L or less than 0.05 mg/L depending on the limit of detection of the analytical method. These similar results are related to the similarity of structures of the category members, and specifically to the presence of long fatty acid chains which confer hydrophobic properties.
Based on the structural similarities between the target and the sources chemicals, water solubility for the target substance was defined to be less than 0.15 mg/L at 20°C and "Ethyl palmitate” was considered to have a low water solubility.
Description of key information
Based on the structural similarities between the target and the sources chemicals, the water solubility for the target substance Ethyl Palmitate was defined to be less than 0.15 mg/L at 20°C.
Key value for chemical safety assessment
- Water solubility:
- 0.15 mg/L
- at the temperature of:
- 20 °C
Additional information
Several members of the category have been tested for their water solubility. The tested substances (isopropyl myristate; fatty acids C16 -18 butyl esters; fatty acids C16 -18, C18 unsat. isobutyl ester; isopropyl isostearate) show water solubility less than 0.15 mg/L or less than 0.05 mg/L depending on the limit of detection of the analytical method. These similar results are related to the similarity of structures of the category members, and specifically to the presence of long fatty acid chains which confer hydrophobic properties. On the basis of a category approach, the water solubility of the target substance was defined to be less than 0.15 mg/L at 20°C and "Ethyl palmitate” was considered to have a low water solubility.
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