Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
not specified
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
other: Data published on ChemIDplus
Title:
ChemIDplus
Bibliographic source:
https://chem.nlm.nih.gov/chemidplus/rn/80012-42-6

Materials and methods

Test animals

Species:
mouse

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
325 mg/kg bw

Applicant's summary and conclusion

Conclusions:
LD50 (oral, mouse) of 1H-Dibenz(c,f)imidazo(1,5-a)azepin-3-amine, 9,13b-dihydro-, hydrobromide CAS n. 80012-42-6 as published on ChemIDplus is 325 mg/kg (source: United States Patent Document. Vol. #4313931).