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EC number: 203-430-9 | CAS number: 106-75-2
Phototransformation in air
Administrative data
Link to relevant study record(s)
Description of key information
After evaporation or exposure to air, the substance and its hydrolysis product diethylene glycol will be rapidly degraded by photochemical processes.
Key value for chemical safety assessment
Additional information
QSAR-disclaimer
In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.
For the assessment of oxydiethylene bis(chloroformate) (CAS 106 -75 -2) and its metabolite diethylene glycol (CAS 111-46 -6) (Q)SAR results were used for phototransformation in air. The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.
Therefore, further experimental studies on phototransformation in air are not provided.
Assessment
Phototransformation in air was calculated using the AOP program v1.92 of EPI Suite v4.11 (US EPA, 2012). The following conditions were used by the program: sensitiser for indirect photolysis: OH; 0.5 E06 OH/cm³, 24 -h day.
Parent compound:
Based on an estimated OH radical rate constant of 17.69E-12 cm³/(molecule*sec), the half-life of oxidiethylene bischloroformate was calculated to be 22 h (BASF SE, 2018). This estimation refers to dry air. In mist, rain, droplets and aerosols, hydrolysis will be the major fate process in air due to the short half-life in aqueous solutions. The substance is not within the applicability domain of the model.
Hydrolysis product diethylene glycol:
Based on an estimated OH-radical rate constant of 22.34E-12 cm³/(molecule*sec), a half-life of 17 h was calculated for the photochemical degradation by OH-radicals (BASF SE, 2015). The substance is within the applicability domain of the model.
It can be concluded that the substance and its hydrolysis product diethylene glycol will be rapidly degraded by photochemical processes after evaporation or exposure to air.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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