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EC number: 259-653-7 | CAS number: 55466-76-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 106 (Adsorption - Desorption Using a Batch Equilibrium Method)
- Version / remarks:
- Tier 1 only
- GLP compliance:
- yes
- Type of method:
- batch equilibrium method
- Media:
- soil
- Radiolabelling:
- no
- Test temperature:
- 25 + 2°C (preliminary study)
- Analytical monitoring:
- yes
- Details on sampling:
- Samples were analysed after a 24 hour equilibration period.
- Details on matrix:
- Soil 2:
Particle size
53 µm – 2 mm: 37.56%
2 µm – 53 µm: 29.37%
<2 µm: 33.08%
pH (1:5 soil to 0.01 M CaCl2 ratio): 7.5
Cation exchange capacity (mEq/100g): 31.1
Organic carbon content (%): 2.4
Total nitrogen (mg/kg): 1693.9
Soil 3:
Particle size
53 µm – 2 mm: 25.88%
2 µm – 53 µm: 46.98%
<2 µm: 17.14%
pH (1:5 soil to 0.01 M CaCl2 ratio): 6.3
Cation exchange capacity (mEq/100g): 26.0
Organic carbon content (%): 3.2
Total nitrogen (mg/kg): 1749.8
Soil 4:
Particle size
53 µm – 2 mm: 55.72%
2 µm – 53 µm: 26.81%
<2 µm: 17.47%
pH (1:5 soil to 0.01 M CaCl2 ratio): 5.6
Cation exchange capacity (mEq/100g): 25.8
Organic carbon content (%): 3.4
Total nitrogen (mg/kg): 2869.7
Soil 5:
Particle size
53 µm – 2 mm: 71.78%
2 µm – 53 µm: 18.90%
<2 µm: 9.32%
pH (1:5 soil to 0.01 M CaCl2 ratio): 5.8
Cation exchange capacity (mEq/100g) 17.5:
Organic carbon content (%): 1.6
Total nitrogen (mg/kg): 1231.8
Soil 7:
Particle size
53 µm – 2 mm: 85.23%
2 µm – 53 µm: 11.94%
<2 µm: 2.83%
pH (1:5 soil to 0.01 M CaCl2 ratio): 2.9
Cation exchange capacity (mEq/100g): 49.2
Organic carbon content (%): 12.0
Total nitrogen (mg/kg): 4367.9 - Details on test conditions:
- 5 soil types were tested, ranging in organic carbon content (2.4 - 12.0%), in a tier 1 assessment, with the aim of selecting the optimal soil / solution ratio. Soil / solution ratios of 1:1, 1:10 and 1:25 were used. Aliquots of 0.01M calcium chloride solution were added to the soil in glass centrifuge tubes.Samples were shaken at 28.5 +- 2.5⁰C in the dark for 18.5 hours, or at 21 +- 1⁰C for 17.5 hours, depending on the soil. Stock solution of the test material was then added to each soil, after which the samples were shaken 21.0 +- 1.0⁰C in the dark for 24 hours, before they were analysed by ICP.
- Sample No.:
- #1
- Type:
- Kd
- Remarks on result:
- not determinable
- Remarks:
- No determination of the adsorption coefficient was possible as the adsorption properties of the test material exceeded the scope of OECD method 106. No significant trend was observed between percentage test material adsorbed and nominal soil to solution ratio, with the exception of soil 4 and to a lesser extent soil 3. As adsorption was not proportional to to the quantity of soil present, calculation of a Kd value was not considered valid.
- Adsorption and desorption constants:
- No determination of the adsorption coefficient was possible as the adsorption properties of the test material exceeded the scope of OECD method 106. No significant trend was observed between percentage test material adsorbed and nominal soil to solution ratio, with the exception of soil 4 and to a lesser extent soil 3. As adsorption was not proportional to to the quantity of soil present, calculation of a Kd value was not considered valid.
However, it can be concluded that the test material does not adsorb strongly to the organic carbon content of the soil as when given the opportunity to adsorb to an increased quantity of soil / organic carbon as the nominal soil / solution ratio altered there was no significant further adsorption. - Recovery of test material:
- Mean percentage recoveries for control solutions with respect to the theoretical fortified concentration ranged from 86.2 to 111%.
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- No determination of the adsorption coefficient was possible as the adsorption properties of the test material exceeded the scope of OECD method 106.
However, it can be concluded that the test material does not adsorb strongly to the organic carbon content of the soil as when given the opportunity to adsorb to an increased quantity of soil / organic carbon as the nominal soil / solution ratio altered there was no significant further adsorption. - Executive summary:
This is a GLP study following OECD 106. However, only a tier 1, 24 hour assessment was conducted, carried out in order to select the optimal soil / solution ratio. No determination of the adsorption coefficient was possible as the adsorption properties of the test material exceeded the scope of OECD method 106. No significant trend was observed between percentage test material adsorbed and nominal soil to solution ratio, with the exception of soil 4 and to a lesser extent soil 3. As adsorption was not proportional to the quantity of soil present, calculation of a Kd value was not considered valid.
However, it can be concluded that the test material does not adsorb strongly to the organic carbon content of the soil as when given the opportunity to adsorb to an increased quantity of soil / organic carbon as the nominal soil / solution ratio altered there was no significant further adsorption.
Reference
Description of key information
No determination of the adsorption coefficient was possible as the adsorption properties of the test material exceeded the scope of OECD method 106. However, it can be concluded that the test material does not adsorb strongly to the organic carbon content of the soil as when given the opportunity to adsorb to an increased quantity of soil / organic carbon as the nominal soil / solution ratio altered there was no significant further adsorption.
Key value for chemical safety assessment
Additional information
O'Connor and Mullee (2006) is a GLP study following OECD 106. However, only a tier 1, 24 hour assessment was conducted, carried out in order to select the optimal soil / solution ratio. No determination of the adsorption coefficient was possible as the adsorption properties of the test material exceeded the scope of OECD method 106. No significant trend was observed between percentage test material adsorbed and nominal soil to solution ratio, with the exception of soil 4 and to a lesser extent soil 3. As adsorption was not proportional to the quantity of soil present, calculation of a Kd value was not considered valid.
However, it can be concluded that the test material does not adsorb strongly to the organic carbon content of the soil as when given the opportunity to adsorb to an increased quantity of soil / organic carbon as the nominal soil / solution ratio altered there was no significant further adsorption.
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