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Diss Factsheets
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EC number: 434-280-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The effect of the test substance on the growth of Pseudoldrchneriella subcapitata was assessed according to OECD Test Guideline 201. The effective loading rate was assessed a 96-Hour period. The Effective Loading Rate that reduced biomass by 50 % (EbL50) was 0.13 mg/L loading rate WAF. The Effective Loading Rate that reduced growth rate by 50 % (ErL50) was 0.17 mg/L loading rate WAF. The No Observed Effect Loading rate at 96 hours was 0.050 mg/L loading rate WAF.
Key value for chemical safety assessment
Additional information
A modification of the standard method for the preparation of aqueous media was performed in view of the difficulties associated with the evaluation of aquatic toxicity of poorly soluble test materials. The organisms were exposed to a Water Accommodated Fraction (WAF) of the test material, which is an approach endorsed by Regulatory Authorities in the EU and elsewhere when the test material is a complex mixture and poorly soluble in water and the auxiliary solvents and surfactants. Exposure is expressed in terms of the original concentration of test material in water at the start of the mixing period (loading rate) irrespective of the actual concentration of test material in the WAF.
The effective loading rate was assessed a 96-Hour period. The Effective Loading Rate that reduced biomass by 50 % (EbL50) was 0.13 mg/L loading rate WAF. The Effective Loading Rate that reduced growth rate by 50 % (ErL50) was 0.17 mg/L loading rate WAF. The No Observed Effect Loading rate at 96 hours was 0.050 mg/L loading rate WAF.
Observations of the cultures microscopically at 96 hours showed that at some concentrations no intact algal cells were observed, although lower concentrations and the control showed no abnormalities. A regrowth experiment was performed after 96 hours exposure to determine whether the algicidal or algistatic effect of the test material. Fresh culture medium was added to ensure that the test concentrations were reduced to below the inhibiting level. Regrowth occurred in all loading rate WAF cultures indicating that the test material was algistatic in effect.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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