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EC number: 260-976-0 | CAS number: 57834-33-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From October 05, 2016 to November 09, 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation))
- GLP compliance:
- yes
- Test organisms (species):
- activated sludge
- Details on inoculum:
- - Source of inoculum/activated sludge: James Wastewater Treatment Plant-Abbotsford BC.
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 3 h
- Nominal and measured concentrations:
- Nominal concentrations: 0 and 1000 mg/L
- Details on test conditions:
- - Aeration: Clean, filtered, oil-free air was provided at ~1.0 L/min
- No. of vessels per concentration (replicates): three
- No. of vessels per negative control (replicates): three
- Sludge concentration: 2.1 g suspended solids/L - Reference substance (positive control):
- yes
- Remarks:
- 3,5-Dichlorophenol (CAS NO.: 591-35-5)
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: aerobic respiration rate
- Results with reference substance (positive control):
- The 3-h EC50 of thr reference substance (3,5-Dichlorophenol) was 16.1 mg/L.
- Validity criteria fulfilled:
- yes
- Conclusions:
- According to OECD 209 test method, the 3-h EC50 of the test substance was greater than 1000 mg/L.
- Executive summary:
This test using the procedures outlined in the Maxxam Study Plan for TOX1613 which is based on the SOP for the OECD 209 (BBY2SOP-00019) and OECD 209 (OECD, 2010). The results of this OECD 209 test for Eversorb EP4 show that all validity criteria were met. The 3-h EC50 of the test substance was greater than 1000 mg/L.
Reference
The oxygen uptake rate of the controls was 22.5 mg O2/h/g dry weight of suspended solids (SS). The coefficient of variation (%CV) of the controls was 11.0%.
Table 1. EC50 and 95% Confidence Intervals for Reference Item Test
3-h EC50 (mg/L) |
95% Confidence Intervals |
± 2SD of Previous Mean |
16.1 |
N/A-20.8 |
5.5-20.7 |
Table 2. Inhibition of Aerobic Respiration Rate by Test Item Eversorb EP4
Sample ID |
Nominal Test Item Concentration (mg/L) |
Slope |
Aerobic Respiration Rate (R, mg O2/L·h) |
Inhibitory Effect on Respiration Rate (%) |
Control #1, Rep A |
0 |
0.7000 |
42.0 |
N/A |
Control #1, Rep B |
0 |
0.6873 |
41.2 |
N/A |
Control #1, Rep C |
0 |
0.8533 |
51.2 |
N/A |
1000 mg/L, Rep A |
1000 |
0.8339 |
50.0 |
-5.9 |
1000 mg/L, Rep B |
1000 |
0.8255 |
49.5 |
-4.9 |
1000 mg/L, Rep C |
1000 |
0.8255 |
49.5 |
-4.9 |
Control #2, Rep A |
0 |
0.8286 |
49.7 |
N/A |
Control #2, Rep B |
0 |
0.8667 |
52.0 |
N/A |
Control #2, Rep C |
0 |
N/A |
N/A |
N/A |
Description of key information
The 3-h EC50 of Eversorb EP4 was greater than 1000 mg/L (OECD TG 209).
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
Additional information
For controls at the end of the test, the oxygen uptake rate was greater than or equal to 20 mg O2/h/g dry weight of suspended solids (SS) and the coefficient of variation (%CV) of the control was less than or equal to 30%. The 3-h EC50 of the reference item (3, 5-Dichlorophenol) was within 2 standard deviations of the previous EC50 values. All test validity criteria were met.Based on the nominal concentrations of Eversorb EP4, the 3-h EC50 for respiration inhibition was greater than 1000 mg/L.
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