Registration Dossier
Registration Dossier
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EC number: 228-033-8 | CAS number: 6091-44-7
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1967
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- Data obtained from an authoritative secondary source.
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Japanese Journal of Pharmacology. Vol. 17, Pg. 475, 1967.
- Year:
- 1 967
- Bibliographic source:
- https://chem.nlm.nih.gov/chemidplus/rn/6091-44-7
Materials and methods
- Principles of method if other than guideline:
- Data cited in ChemIDplus database. Only result is provided on the database.
- GLP compliance:
- no
Test material
- Reference substance name:
- Piperidinium chloride
- EC Number:
- 228-033-8
- EC Name:
- Piperidinium chloride
- Cas Number:
- 6091-44-7
- Molecular formula:
- C5H11N.ClH
- IUPAC Name:
- piperidinium chloride
- Test material form:
- solid: crystalline
- Details on test material:
- No other details on test material were provided.
Constituent 1
- Specific details on test material used for the study:
- No specific details on test material used for the study is provided. Only result is provided in the database.
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
- Details on test animals or test system and environmental conditions:
- No other information provided in the data source.
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- not specified
- Details on exposure:
- No other information provided in the data source.
- Doses:
- No data
- No. of animals per sex per dose:
- No data
- Control animals:
- not specified
- Details on study design:
- No other information provided in the data source.
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- ca. 330 mg/kg bw
- Based on:
- not specified
- Remarks on result:
- other: No other information provided in the data source.
- Mortality:
- No data
- Clinical signs:
- No data
- Body weight:
- No data
- Gross pathology:
- No data
- Other findings:
- - CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
- CYANOSIS
Applicant's summary and conclusion
- Conclusions:
- The LD50 of mouse is found to be 330 mg/kg through intraperitoneal administration of piperidine hydrochloride.
- Executive summary:
The LD50 of mouse is found to be 330 mg/kg through intraperitoneal administration of piperidine hydrochloride.
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