Registration Dossier
Registration Dossier
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EC number: 231-954-8 | CAS number: 7782-41-4
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The toxicity of fluorine to microorganisms is derived from experimental data with its degradation product fluoride.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 510 mg/L
Additional information
No aquatic toxicity studies with fluorine are available or can be performed as in contact with water fluorine reacts instantly and violently under formation of hydrogen fluoride. Hydrogen fluoride will further react to fluoride. Therefore available data from studies with fluoride are given as indication of the aquatic toxicity of fluorine.
In the EU Risk Assessment Report for hydrogen fluoride several studies with micro-organisms are reported (EU-RAR, 2001). The long-term NOEC-values for microorganisms range from 7.1 to 510 mg/L. In the EU-RAR it is concluded that only the results of an activated sludge test (3h-EC10 value of 510 mg fluoride/L) and a test on Pseudomonas putida (NOEC of 231 mg fluoride/L) can theoretically be used for deriving a PNEC for microorganisms. As the EC10 -value of 510 mg fluoride/L from the activated sludge test brings about the lowest PNEC, this study is concluded to be critical. As no new data have become available since the EU-RAR, this conclusion is adopted for this substance evaluation.
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