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EC number: 248-983-7 | CAS number: 28348-53-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Qualifier:
- according to guideline
- Guideline:
- EPA OTS 797.1300 (Aquatic Invertebrate Acute Toxicity Test, Freshwater Daphnids)
- GLP compliance:
- yes
- Specific details on test material used for the study:
- CAS Number: 28348-53-0
Identity: Cumene sulfonic acid, sodium salt
Purity: 45%
Remarks: Substances tested are aqueous solutions; % purity
equates to chemical content - Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- Concentrations: Nominal: 100, 180, 320, 560 and 1000 mg/L (no vehicle);
untreated controls. Nominal concentrations have not been corrected for
sample purity.
Test conditions: Static without aeration; at 20 ± 2 °C in 250 mL glass vessels
containing 200 mL of medium of hardness 146 mg/L (CaCO3) and pH 8.2;
16 hours light, unfed.
Physical measurements: At 0 and 48 hours: overall ranges for pH 8.2-8.4; O2
86-89%; temperature 20-21 °C.
Observations: Immobility/symptoms at 24 and 48 hours. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Species: Daphnia magna, <24 hours old
Number of daphnids: 10/beaker, 2 beakers/treatment. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Hardness:
- 146 mg/L (CaCO3
- Test temperature:
- 20 ± 2 °C
- pH:
- 8.2
- Dissolved oxygen:
- O2
86-89% - Salinity:
- NR
- Nominal and measured concentrations:
- Concentrations: Nominal: 100, 180, 320, 560 and 1000 mg/L (no vehicle);
untreated controls. Nominal concentrations have not been corrected for sample purity - Details on test conditions:
- Test conditions: Static without aeration; at 20 ± 2 °C in 250 mL glass vessels containing 200 mL of medium of hardness 146 mg/L (CaCO3) and pH 8.2;
16 hours light, unfed.
Physical measurements: At 0 and 48 hours: overall ranges for pH 8.2-8.4; O2 86-89%; temperature 20-21 °C.
Observations: Immobility/symptoms at 24 and 48 hours. - Reference substance (positive control):
- no
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 48-h EC50 >1000 mg/L (equivalent to 450 mg/L active ingredient considering the 45% sample purity).
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 450 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- act. ingr.
- Basis for effect:
- mobility
- Remarks on result:
- other: 48-h EC50 >1000 mg/L (equivalent to 450 mg/L active ingredient considering the 45% sample purity).
- Details on results:
- A 48 h EC50 > 1000 mg/L has been determined for the effects of the test substance on immobilation of the Daphnia magna (48-h EC50 >1000 mg/L (equivalent to 450 mg/L active ingredient considering the 45% sample purity)
- Validity criteria fulfilled:
- yes
- Conclusions:
- A 48 h EC50 > 1000 mg/L has been determined for the effects of the test substance on immobilation of the Daphnia magna (48-h EC50 >1000 mg/L (equivalent to 450 mg/L active ingredient considering the 45% sample purity).
The test material is not acutely toxic to Daphnia magna at up to 1000 mg/L, corresponding to 450 mg/L active ingredient - Executive summary:
A 48 h EC50 > 1000 mg/L has been determined for the effects of the test substance on immobilation of the Daphnia magna (48-h EC50 >1000 mg/L (equivalent to 450 mg/L active ingredient considering the 45% sample purity).
The test material is not acutely toxic to Daphnia magna at up to 1000 mg/L, corresponding to 450 mg/L active ingredient
Reference
Results
Unit: mg/L
|
|
Nominal Concentration (mg/L) |
|||||
Parameter |
Time [hours] |
0 |
100 |
180 |
320 |
560 |
1000 |
Immobility [%] |
48 |
0 |
0 |
0 |
0 |
5 |
0 |
Symptoms |
48 |
No treatment related effects |
Description of key information
A 48 h EC50 > 1000 mg/L has been determined for the effects of the test substance on immobilation of the Daphnia magna (48-h EC50 >1000 mg/L (equivalent to 450 mg/L active ingredient considering the 45% sample purity).
The test material is not acutely toxic to Daphnia magna at up to 1000 mg/L, corresponding to 450 mg/L active ingredient
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 450 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 45 mg/L
Additional information
The available data for saltwater invertebrates a are limited and to obtaine the value for PNECs for saltwaters is taken account a assesment factor 10 to extrapolate to NOEC following the “Guidance on Information Requirement and Chemical Safety Assessment R.10: Characterisation of dose [concentration]- response for environment”and “Table R.10-5 Assessment factors proposed for deriving PNEC water for saltwater for different data sets”, to account for the possibility that greater taxonomic diversity in the marine environment makes it likely that some marine taxa may be more sensitive than the most sensitive freshwater taxa
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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