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EC number: 259-423-6 | CAS number: 54982-83-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Abiotic degradation:
Air: Based on estimation with the QSAR model AopWin, the substance undergoes in air rapid degradation after reaction with hydroxyl radicals with a DT50 value of 8.18 hours, using the SMILES ((O=C(OCCOC(=O)CCCCCCCCC1)C1). No ozone reaction estimation could be made with AopWin. The estimated half-life is much shorter than 2 days, which is the cut off time for reaching the stratosphere. The substance is therefore not expected to reach the stratosphere and is not a long-range transported chemical in air according to the UNECE criteria (http://www.unece.org/fileadmin/DAM/env/documents/2000/ece/eb/ece%20eb%20air.60.e.pdf). This means that the substance does not have an ozone depletion potential because it does not contain halogens and does not have the potential to reach the stratosphere (EU CLP, EC 1272/2008 and its amendments).
Water: No experimental hydrolysis information is available. A test was not needed because Zenolide is readily biodegradable. Zenolide is an ester and therefore some hydrolysis may be expected.
Biotic degradation: In the key screening study according to OECD TG 301B 100% biodegradation was found after 28 days. This study shows that the substance is readily biodegradable.
Bioaccumulation: The BCF of Zenolide is estimated to be 156 l/kg based on read across with Verdox (Cas no 20298-69-5). When calculating the BCFs for aquatic and terrestrial organisms using QSARs of Veith et al. (1979) and Jager (1998), both incorporated in the EUSES model, BCF values of 253 and 54.4 L/kg w.w., respectively, were found.
Transport and distribution:
Adsorption: The adsorption coefficient (Koc) of the substance has been determined to be 1800 L/kg (log Koc: 3.3), using the HPLC screening method (OECD 121).
Henry's law constant: To assess the volatilisation potential of the substance a Henry's law constant was calculated which gave a result of 0.0427 Pa.m3/mol (at 12 °C). Volatilisation from water will therefore be minimal.
Environmental distribution modelling: Based on Level III environmental distribution modelling using EPISUITE (v4.1 and assuming equal and continuous releases to air, water and soil) using the CAS number 54982 -83 -1 and the measured log Kow, water solubility and vapour pressure as input, it is estimated that the majority of the substance released to the environment will partition mainly into soil (73.6%) and water (24.7%) with small amounts to air (1.26%) and sediment (<1%). The ready biodegradability is not considered here.
The SimpleTreat model, which is incorporated in EUSES, simulates the distribution of the substance in a Sewage Treatment Plant based on vapour pressure, water solubility, log Koc and ready biodegradability. The model predicts that 74.1% of the substance will be degraded and that the remaining substance will partition to sludge (14.9%) and water (11%).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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