Registration Dossier
Registration Dossier
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EC number: 250-807-9 | CAS number: 31795-24-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Short-term toxicity to fish: 96 hr LC50 >500 mg/l (nominal) (highest concentration tested) (EU Method C.1 (Acute Toxicity for Fish), read-across from an analogous/structurally related substance, triethoxy(methyl)silane (CAS 2031-67-6). The LC50 is equivalent to >264 mg/l when expressed in terms of the silanol hydrolysis product.
Key value for chemical safety assessment
Additional information
The properties of this substance can be read-across from tests carried out for triethoxy(methyl)silane (CAS 2031-67-6), which hydrolyses rapidly to give methylsilanetriol and ethanol. The properties of ethanol are well characterised; it is non-toxic to the environment and it is considered unlikely that its presence would significantly affect the results of tests performed with triethoxy(methyl)silane.
There are no reliable short-term fish toxicity data available for potassium methylsilanetriolate (CAS 31795-24-1), therefore good quality data for an appropriate structural analogue, triethoxy(methyl)silane (CAS 2031-67-6), have been read across. The silanol hydrolysis product of the surrogate substance is the same substance as that upon which this chemical safety assessment is based, i.e. methylsilanetriol (CAS 2445-53-6). The other hydrolysis product of the surrogate substance is ethanol.
A 96-h LC50 value of >500 mg/l and NOEC of >=500 mg/l (nominal) (highest concentration tested) have been determined for the effects of triethoxy(methyl)silane (CAS 2031 -67 -6) on mortality of Brachydanio rerio. In view of the test media preparation method/exposure regime it is likely that the test organisms were exposed predominantly to the hydrolysis products of the tested substance. The results may be expressed in terms of concentration of the hydrolysis product, methylsilanetriol, by applying a molecular weight correction: (MW of silanol = 94.14 / MW of parent = 178.31) * (CONCENTRATION OF PARENT = >500) = >264 mg/l as methylsilanetriol.
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