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Diss Factsheets
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EC number: 217-162-5 | CAS number: 1759-53-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- Cyclopropane carboxylic acid
- Type of composition:
- legal entity composition of the substance
- State / form:
- liquid
- Reference substance:
- Cyclopropane carboxylic acid
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Cyclopropane carboxylic acid (CPCA) - CAS No. 1759 – 53 -1
The environmental assessment using EPIWIN of shows that the substance Cyclopropane carboxylic acid - CAS No. 1759 – 53 -1 does not meet the criteria for classification as PTB or vPTB.
It is expected that the substance being a carboxylic acid will readily dissociate in water. The substance has a very low Log Kow measured at: Log Kow 1.68. This low Log Kow is an indication that the substance is likely to remain in water indicating not be B or vB. In addition the bioaccumulation factor (predicted from valid EPI suit) is extremely low at 3.162 L/kg. This is well below the > 2000 L/kg threshold which again indicated not B or vB.
With respect to the persistency the predicted (EPI suit) Biowin 3 degradation rate is 3.3 and is a strong indication that the substance will biodegrades fast (days – weeks). The Biowin 2 probability is above 0.5 (estimated probability 0.99) again giving a further indication that the substance will biodegrade fast. The third key prediction from the EPI suit results, Biowin 5, indicates a probability above 0.5 (estimated probability 0.689) giving an indication that the substance will again biodegrade readily. In summary the Biowin 3 (ultimate survey model) results in ‘days to weeks’ and the Biowin 5 (MITI linear model) has a probability above 0.5 and so the prediction is yes, the substance will readily biodegrade . The overall assessment of the EPI suit predictions is that the substance is not P or vP.
Cyclopropane carboxylic acid is not classified as carcinogenic (cat 1A or 1B), cell mutagenic (category 1A or 1B) or toxic for reproduction (category 1A, 1B or 2) in accordance with EC No. 1272/2008. The substance has been listed in Annex III but this is no firm indication that the substance should be classified as CMR. Based on all of the above the substance is not PTB.
Further PTB assessment is not thought necessary.
The substance is not classified as PBT therefore there route of exposure is not relevant
- Likely routes of exposure:
No routes of exposure as it is not PBT
Reference
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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