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EC number: 204-072-6 | CAS number: 115-21-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Effect on fertility: via oral route
- Dose descriptor:
- NOAEL
- 1 000 mg/kg bw/day
Additional information
There are no adequate reproductive toxicity data on trichloro(ethyl)silane or its hydrolysis product, ethylsilanetriol, so good quality data for the related substance methyltrimethoxysilane (MTMS) has been used to assess the reproductive effects of trichloro(ethyl)silane.
Trichloro(ethyl)silane hydrolyses rapidly in contact with water (half-life <1 minute at pH 7), generating HCl and ethylsilanetriol. Methyltrimethoxysilane (MTMS, CAS 1185 -55 -3) hydrolyses more slowly at pH 7 (half-life ca. 2 hours), but under acidic conditions such as in the stomach following ingestion, much more rapid hydrolysis can be expected based on experience with other methoxysilanes. The relevant hydrolysis products are methanol and methylsilanetriol. The silanol hydrolysis products are therefore very similar in chemical structure, the only difference being the replacement of -C2H5 with -CH3. Both have high water solubility and very low logKow(log Kow-1.9 and -2.4, respectively). They are therefore expected to have similar toxicological behaviour. Data obtained via the oral route for MTMS are therefore considered appropriate for read-across to trichloro(ethyl)silane.
Short description of key information:
No reproductive toxicity data are available for trichloro(ethyl)silane, therefore data for the related substance methyltrimethoxysilane, CAS 1185-55-3, have been read-across. No effects on reproductive parameters were observed in an OECD 422 screening study (Dow Corning, 2005) up to the highest dose tested. The NOAEL was therefore greater than or equal to 1000 mg/kg bw/day.
Effects on developmental toxicity
Description of key information
No developmental toxicity data are available for trichloro(ethyl)silane, therefore data for the related substance methyltrimethoxysilane, CAS 1185-55-3, have been read-across. No effects on reproductive parameters were observed in an OECD 422 screening study (Dow Corning, 2005) up to the highest dose tested. The NOAEL was therefore greater than or equal to 1000 mg/kg bw/day.
Effect on developmental toxicity: via oral route
- Dose descriptor:
- NOAEL
- 1 000 mg/kg bw/day
Additional information
There are no adequte developmental toxicity data on trichloro(ethyl)silane or its hydrolysis product, ethylsilanetriol, so good quality data for the related substance methyltrimethoxysilane (MTMS) has been used to assess the developmental toxicity of trichloro(ethyl)silane.
Trichloro(ethyl)silane hydrolyses rapidly in contact with water (half-life <1 minute at pH 7), generating HCl and ethylsilanetriol. Methyltrimethoxysilane (MTMS, CAS 1185 -55 -3) hydrolyses more slowly at pH 7 (half-life ca. 2 hours), but under acidic conditions such as in the stomach following ingestion, much more rapid hydrolysis can be expected based on experience with other methoxysilanes. The relevant hydrolysis products are methanol and methylsilanetriol. The silanol hydrolysis products are therefore very similar in chemical structure, the only difference being the replacement of -C2H5 with -CH3. Both have high water solubility and very low logKow(log Kow-1.9 and -2.4, respectively). They are therefore expected to have similar toxicological behaviour. Data obtained via the oral route for MTMS are therefore considered appropriate for read-across to trichloro(ethyl)silane.
Justification for classification or non-classification
The available read-across data on methyltrimethoxysilane do not suggest that there is a need to classify trichloro(ethyl)silane for adverse effects on reproduction or development.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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