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EC number: 919-583-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: No GLP study but other quality assurance
Cross-reference
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Remarks:
- other quality assurance
- Type of method:
- flask method
Test material
- Reference substance name:
- cupro, copper processing
- EC Number:
- 919-583-6
- IUPAC Name:
- cupro, copper processing
- Details on test material:
- Representative samples collected according to Standard sampling protocol of the REACH Copper Consortium (see attach to Iuclid 1.4)
B15, sample description: Cupro, Representative charge, Metallic fraction (composite, grinded), sample code: MC_B15_54_1A_comp_0904, lab code: 09TT02932
B15, sample description: Cupro, Representative charge, metallic fraction (representative pieces, lumps), sample code: MC_B15_54_1B_comp_0904, lab code: 09TT02790
B15, sample description: Cupro, Representative charge, Oxidic fraction (ie powder) (composite, homogenized), sample code: MC_B15_54_2_comp_0904, lab code: 09TT02933
B15, sample description: Cupro, Al-specific charge, Metallic fraction (composite, grinded), sample code: MC_B15_Al_3A_comp_0906, lab code: 09TT05024
B15, sample description: Cupro, Al-specific charge, Metallic fraction (representative pieces, lumps), sample code: MC_B15_Al_3B_comp_0906, lab code:09TT04859
Constituent 1
Results and discussion
- Details on results:
- 42 mg/l Pb and 19 mg/l Ca were dissolved from the sample 09TT02933. Otherwise the samples were low soluble.
Any other information on results incl. tables
The preliminary test did not indicate any solubility for the studied samples. Approximately 5 g sample and 100 ml water were taken to each test. Specific weighed amounts are given in Appendices A-C of the study report.
The classical definition of water solubility is not applicable to multi-component i.e. complex substances. The usually accepted meaning of solubility in such cases was the composition of the aqueous solution formed at equilibrium under a defined set of conditions. It was however not always possible to establish that equilibrium of all components is achieved. Therefore, time and type of agitation of test vessels have been described (see 5.4).
The shaking time was for 09TT02790 and 09TT04859 14-16 days and for 09TT02933 13-15 days. After that each sample was equilibrated for 24 h time. Table 6 presents measured pH range and average metal concentrations for the samples. Substances with solubility <10 mg/l are considered low-soluble and those with solubility <1 mg/l are considered poorly soluble.
42 mg/l Pb and 19 mg/l Ca were dissolved from the sample 09TT02933. Otherwise the samples were low soluble. The standard method involves three tests, which is not enough for a statistical analysis.
Table 6: Average water solubility calculated from the 13-15 and 14-16 days shaking tests.
|
Sample code |
09TT02790 |
09TT02933 |
09TT04859 |
|
|
Average or range |
Average or range |
Average or range |
pH |
|
8.67-9.48 |
10.40-10.85 |
5.79-8.89 |
ICP Ag |
mg/l |
<1 |
<1 |
<1 |
ICP Al |
mg/l |
<0.2 |
2 |
<0.2 |
ICP As |
mg/l |
<0.21 |
<0.2 |
<0.2 |
ICP Ca |
mg/l |
- |
19 |
- |
ICP Co |
mg/l |
<0.1 |
<0.2 |
<0.2 |
ICP Cr |
mg/l |
<0.1 |
<0.2 |
<0.1 |
ICP Cu |
mg/l |
<1 |
<0.2 |
<0.2 |
ICP Fe |
mg/l |
<0.2 |
<0.2 |
<1 |
ICP K |
mg/l |
<2 |
<5 |
<5 |
ICP Mg |
mg/l |
<0.2 |
<0.2 |
<0.1 |
ICP Mn |
mg/l |
<0.1 |
<0.2 |
<0.1 |
ICP Na |
mg/l |
<2 |
<3 |
<1 |
ICP Ni |
mg/l |
1.4 |
<0.2 |
1.6 |
ICP Pb |
mg/l |
<0.2 |
42 |
<0.5 |
ICP S |
mg/l |
<5 |
<5 |
<5 |
ICP Sb |
mg/l |
0.4 |
<0.2 |
<0.2 |
ICP Se |
mg/l |
<0.2 |
<0.2 |
<0.2 |
ICP Si |
mg/l |
5 |
0.4 |
4 |
ICP Sn |
mg/l |
<0.2 |
<0.2 |
<0.2 |
ICP Te |
mg/l |
<0.2 |
<0.2 |
<0.5 |
ICP Zn |
mg/l |
<0.5 |
- |
<0.2 |
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): other: insoluble in preliminary test
Preliminary test did not indicate any solubility of the substance. Flask method test was performed on representative sample of the UVCB, a complex metal containing substance. Validity of the reported results confirmed by Harlan Lab (V. Gretton, 2010) - Executive summary:
Classic definition of solubility does not apply to the UVCB, who is a complex metal containing substance. The usually accepted meaning in that case is (according to ECHA Guidance on information requirements and chemical safety assessment Chapter R.7a) "the composition of the aqueous solution formed at equilibrium under a defined set of conditions". Temperature and the amount of substance added per unit volume of water (i.e. the loading) are the main factors to consider. It was not always possible to establish equilibrium of all components; therefore, time and type of agitation of the vessels have been described. Aqueous solubility was reported in mg/l.
For this UVCB, preliminary result demonstrated that substance is poorly soluble (i.e. insoluble) in water. Major results from the additional flask test were: approximately 5 g sample and 100 ml water were taken to each test; the shaking time was 14-16 days and/or 13-15 days, after that each sample was equilibrated for 24 h time. Under these conditions, solubility of the constituents remains low, except for Ca, K, Na, S, and Si (low to poor), as well as Ni and Pb (low). The pH of the solutions varied from 5.8 to 8.9, 8.7 to 9.5 and 10.4 to 10.8, respectively.
Under these conditions, the report acknowledges that stated solubility may be higher than reality for some samples (e.g. due to abrasion, difficult to remove tiny undissolved particles, etc)
The reported results from OECD 105 are therefore indicative for the behaviour of the UVCB in water. For the purpose of assessing environmental fate and behaviour of this difficult to test complex metal containing substance, Transformation/dissolution test would however be more appropriate.
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