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Diss Factsheets
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EC number: 945-924-3 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 29 Jul - 26 Aug 1999
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test)
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- other: Secondary effluent
- Details on inoculum:
- - Source of inoculum/activated sludge: Secondary effluent from a domestic sewage treatment plant (Kläranlage Odenthal, Germany). Date of collection: 23 Jul 1999
- Laboratory culture: no
- Pretreatment: separation of coarse particles by filtration
- Storage length: 6 days (aerated)
- Concentration of effluents in reaction mixture: 5 mL/L - Duration of test (contact time):
- 28 d
- Initial conc.:
- 2.8 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to guideline
- Test temperature: 20 ± 1 °C
- Continuous darkness: yes
TEST SYSTEM
- Number of culture flasks/concentration: 2 replicates
SAMPLING
- Sampling frequency: On day 7, 14, 21 and 28
- Sampling method: O2 depletion in test vessels was measured
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes, 2 replicates
- Abiotic sterile control: no
- Toxicity control: yes, 2 replicates
- Other: reference substance: 2 replicates - Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
- Details on results:
- 0% degradation after 28 d, 60% pass level and 10-day window were not met.
- Results with reference substance:
- 80% after 28 d, 60% pass level was reached.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- This study indicates that the substance is not readily biodegradable (0% after 28 d (O2 consumption, EU method C.4-E)).
Reference
Table 1: % degradation of the test substance, reference substance and in the toxicity control
day |
% degradation test substance |
% degradation reference substance |
% degradation toxicity control |
||||||
1 |
2 |
Mean |
1 |
2 |
Mean |
1 |
2 |
Mean |
|
7 |
0 |
0 |
0 |
63 |
63 |
63 |
26 |
25 |
26 |
14 |
1 |
0 |
1 |
68 |
72 |
70 |
30 |
31 |
31 |
21 |
0 |
0 |
0 |
79 |
77 |
78 |
33 |
32 |
33 |
28 |
0 |
0 |
0 |
80 |
80 |
80 |
34 |
33 |
34 |
The toxicity control attained 31% degradation after 14 d indicating that the test substance is not inhibitory to the inoculum (degradation > 25% based on ThOD).
Description of key information
Not readily biodegradable: 0% after 28 d (O2 consumption, EU method C.4-E)
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
One experimental study is available investigating the ready biodegradability of the test substance. The study was performed according to the EU Method C.4-E (GLP). Secondary effluent from a domestic sewage treatment plant was used as inoculum. After 28 d, 0% degradation of the test substance was recorded based on O2-consumption. Thus, the test substance is not readily biodegradable according to the OECD criteria. A toxicity control containing both, reference substance and test substance, did not indicate inhibitory effects to the inoculum (31% degradation after 14 d; trigger value of 25% biodegradation in the toxicity control was reached).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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