Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
GLP compliance:
no
Type of method:
gas saturation method

Test material

Constituent 1
Chemical structure
Reference substance name:
6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
EC Number:
255-464-9
EC Name:
6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
Cas Number:
41621-49-2
Molecular formula:
C12H17NO2.C2H7NO
IUPAC Name:
6-cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one, compound with 2-aminoethanol (1:1)
Test material form:
solid: particulate/powder

Results and discussion

Vapour pressureopen allclose all
Test no.:
#1
Temp.:
20 °C
Vapour pressure:
0 Pa
Test no.:
#2
Temp.:
35 °C
Vapour pressure:
0 Pa
Test no.:
#3
Temp.:
50 °C
Vapour pressure:
0 Pa

Any other information on results incl. tables

Since no detectable signal of the Ciclopirox-EDTA-TB (III) complex were found in the sorbent extracts using a specific HPLC/FLD method, a vapour pressure value was calculated from LOQ level standard concentration (i.e. 0.6 µg/ml) and the vapour pressure value of Ciclopirox olamine referred as lower than this results.

Applicant's summary and conclusion

Conclusions:
Vapor pressure of Ciclopirox olamine is lower than 0.00014 Pa at 20°C.