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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- July 09, 2007 - August 01, 2007
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: study conform with Directive 92/69/EEC, C.2, OECD Guideline No. 202
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Details on test material:
- Identity: AES
Batch No.: LSF7
Purity: 80.3%
Expiration date: February 15, 2008
Solubility in water: Very soluble
Stability in water: 30 days
Aggregate state / physical
form at room temperature: Solid
Specific information: Slightly hygroscopic
Storage conditions: In a refrigerator at about 4 °C
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- For the determination of the actual test item concentrations, duplicate samples were taken from each treatment before the start of the test and at the end of the test . For the 48-hour stability samples, the contents of the respective replicates were combined prior to sampling.
All samples were stored deep-frozen (at about -20 °C) immediately after sampling.
The concentration of the test item AES was analytically measured in the duplicate test medium samples of the single test concentration taken at the start and the end of the test.
From the control, only one of the duplicate samples was analyzed from each of the sampling times.
Test solutions
- Vehicle:
- no
- Details on test solutions:
- The test medium was prepared by dissolving 30.1 mg of test item completely in 300 mL of test water intense stirring for 15 minutes at room temperature. The test medium was prepared just before introduction of the daphnids (i.e., start of the test).
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Strain Straus
Source Bred in RCC Ltd ( originally supplied by University of Sheffield / UK in 1992)
Age Less than 24 hours old and were not first brood progeny
Breeding method In reconstituted water of the quality identical to the water used in the tests and under the same temperature and light conditions to those of the tests.
Kind of food Not specified in the report
Amount of food Not specified in the report
Feeding frequency Not specified in the report
Pretreatment Not specified in the report
Feeding of animals during test No feeding
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Post exposure observation period:
- The daphnids were observed for immobility after 24 and 48 hours of exposure.
Test conditions
- Hardness:
- Water Hardness: 250 as CaCO3
- Test temperature:
- 20°C
- pH:
- 7.8 to 8.0
- Dissolved oxygen:
- 8.5 mg/L
- Nominal and measured concentrations:
- 100 mg / L
- Details on test conditions:
- Test temperature 20 °C
Dissolved oxygen 8.5 mg/L
pH 7.9
Adjustment of pH No
Aeration of dilution water No
Quality/Intensity of irradiation Light intensity during the light period was between approximately 490 and 650 Lux.
Photoperiod 16 h of fluorescent light and 8 h of darkness cycle with a 30 minute transition period was used. - Reference substance (positive control):
- yes
- Remarks:
- potassium dichromate
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 94%
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- >= 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: 94%
- Details on results:
- No remarkable observations, clear test medium.
- Results with reference substance (positive control):
- In the control and at the concentration of 100 mg/L, no immobilized daphnids were determined during the test period of 48 hours
- Reported statistics and error estimates:
- None.
Any other information on results incl. tables
Effect of AES on the mobility of Daphnia magna
Test item concentration (mg/L) |
No. of daphnids tested |
Immobilized daphnids after 24 hours No. |
% |
Immobilized daphnids after 48 hours No. |
% |
Control 100 |
20 20 |
0 0 |
0 0 |
0 0 |
0 0 |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The validity criteria can be considered as fulfilled and therefore the toxicity values are considered reliable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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