Registration Dossier
Registration Dossier
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EC number: 229-398-6 | CAS number: 6507-79-5
Endpoint summary
Administrative data
Description of key information
Additional information
Acute short-term administration on fish:
The assessment was based on one study made in 1974 and conducted according to Ciba Geigy AG internal method 11. The purity of substance was 90 %. Only a short abstract is available. Eight Rainbow trout were tested with 2, 20 and 100 mg/l of test item. The substance shows a LC50 = 6.3 mg/l. This study was judged as low reliable, therefore the test results were not considered for the Classification.
Acute short-term administration on invertebrates:
The assessment is based on a single study made in 1994 and conducted according to The OECD guideline 202 and EU method C.2. This study was performed in according to the GLP Principles. The acute toxicity to Daphnia magna was determined during a 48 hour static test. The test article concentrations in the analysed test media were in the range of 94.6 - 98.4 % of the nominal values. Therefore, under test conditions the test article was sufficiently stable, and the purity was the 90 %. The substance shows the following values:
NOEC(48h) = 9.7 mg/l
EC50(48h) = 48.9 mg/l
EC100(48h) > 172.1 mg/l
Acute short-term administration on aquatic plants.
The test perfromed according to OECD 221, acute toxicity to aquatic plants (Lemna minor) showed some effect.
The EC50 growth rate related to frond number is 47.1 mg/l.
NOEC growth rate related to frond number is 2.43 mg/l.
The test substance is very soluble in pure (deionised) water ( about 107.88 g/l), none sedimentation has been observed during the tests. The substance shows a high toxicity level as shown during the observation period for the tested trophic levels.
According to the table 4.1.0 of the CLP Regulation (EC n. 1272/2008), a substance for wich adequate chronic toxicity data are not available shall be classified as Aquatic Chronic 3 when:
96 hr LC50 (for fish) > 10 <= 100 mg/l and/or
48 hr EC50 (for crustacea) > 10 <= 100 mg/l and/or
72 or 96 hr ErC (for algae or other aquatic plants) > 10 <= 100 mg/l
and the substance is not rapidly degradable and/or the experimentally determined BCF ≥ 500 (or, if absent, the log K ow ≥ 4)
Taking into account the information available for the target substance, the classification proposed is Aquatic Chronic 3.
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